Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387202 | 0.82 | NPSR1 (0.43) | MAPTNPSR1CES2CES1ALDH1A1 | |
| SCHEMBL204288 | 0.82 | NPSR1 (0.43) | MAPTNPSR1CES2CES1ALDH1A1 | |
| SCHEMBL508790 | 0.82 | NPSR1 (0.43) | MAPTNPSR1CES2CES1ALDH1A1 | |
| SCHEMBL9148153 | 0.76 | MAPT (0.42) | MAPTCES2CES1ALDH1A1TSHR | |
| SCHEMBL202695 | 0.74 | KMT2A (0.39) | MAPTNPSR1ALDH1A1TSHRGLA | |
| SCHEMBL9422275 | 0.72 | KMT2A (0.40) | MAPTNPSR1ALDH1A1TSHRGLA | |
| SCHEMBL9151416 | 0.72 | MAPT (0.42) | MAPTCES2CES1ALDH1A1TSHR | |
| SCHEMBL10508349 | 0.72 | ALDH1A1 (0.41) | MAPTNPSR1ALDH1A1TSHRGLA | |
| SCHEMBL7938546 | 0.71 | NPSR1 (0.50) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL8755379 | 0.69 | MAPT (0.47) | MAPTALDH1A1TSHRGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381321-B1 | Method for forming a crosslinkable pressure-sensitive adhesive construction containing an aminoxysilicon compound and an amidosilicon compound | DOW CORNING (US) | 1995-01-04 | — | — | EP | disclosed |
| EP-0271296-B1 | SYNTACTIC SEALANTS | DOW CORNING CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5086103-A | Pressure-sensitive composition containing an aminoxysilicon compound | DOW CORNING CORPORATION (US) | 1992-02-04 | — | — | US | disclosed |
| US-5051472-A | An addition polymer or a polyurethane rubber with a aminooxysilicon compound and an amidosilicon or amidosilane | DOW CORNING CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0381321-A2 | Method for forming a crosslinkable pressure-sensitive adhesive construction containing an aminoxysilicon compound and an amidosilicon compound | DOW CORNING CORPORATION (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0271296-A2 | Syntactic sealants | DOW CORNING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |