Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274152 | 0.80 | HTR2B (0.43) | TSHRKMT2ACYP2D6CYP2C9ALOX15 | |
| SCHEMBL20274217 | 0.79 | HTR2B (0.39) | TSHRKMT2ADPP4CYP2D6CYP2C9 | |
| SCHEMBL20274139 | 0.77 | HRH4 (0.47) | KDM4EALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL20274204 | 0.77 | EPHX2 (0.40) | SIGMAR1KDM4EALDH1A1TSHRKMT2A | |
| SCHEMBL20651225 | 0.75 | HTR2B (0.43) | KDM4EALDH1A1KMT2ALMNAHTT | |
| SCHEMBL20274216 | 0.75 | HTR2B (0.46) | KDM4EALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL20274133 | 0.74 | MAOA (0.51) | SIGMAR1HTR2BHTR1A | |
| SCHEMBL23335850 | 0.73 | PDE7B (0.40) | KDM4EALDH1A1TSHRCYP2D6CYP2C9 | |
| SCHEMBL20274136 | 0.72 | MEN1 (0.42) | TSHRKMT2ACYP2D6CYP2C9ALOX15 | |
| SCHEMBL20274183 | 0.72 | HTR2B (0.54) | KDM4EALDH1A1KMT2ALMNAHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |