Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651225 | 0.85 | HTR2B (0.43) | HTR2BDRD2HTR1AALDH1A1LMNA | |
| SCHEMBL20274152 | 0.82 | HTR2B (0.43) | HTR2BDRD2HTR1AMEN1KMT2A | |
| SCHEMBL20274139 | 0.82 | HRH4 (0.47) | HTR2BDRD2HTR1AGAAALDH1A1 | |
| SCHEMBL20274133 | 0.80 | MAOA (0.51) | HTR2BHTR1AMAOA | |
| SCHEMBL20274217 | 0.77 | HTR2B (0.39) | HTR2BDRD2HTR1AMEN1KMT2A | |
| SCHEMBL20274192 | 0.76 | HRH3 (0.45) | MAOA | |
| SCHEMBL20274216 | 0.75 | HTR2B (0.46) | HTR2BDRD2HTR1AALDH1A1LMNA | |
| SCHEMBL15724778 | 0.74 | ALDH1A1 (0.56) | HTR2BDRD2HTR1AALDH1A1LMNA | |
| SCHEMBL11343183 | 0.73 | GRIN2B (0.66) | DRD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL119001 | 0.73 | CYP2A6 (0.51) | GAAALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |