Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274140 | 0.88 | ALDH1A1 (0.48) | KMT2ACYP2D6TSHRCYP2C19 | |
| SCHEMBL20274170 | 0.86 | L3MBTL1 (0.44) | MEN1KMT2A | |
| SCHEMBL20274152 | 0.75 | HTR2B (0.43) | MEN1KMT2ACYP2D6CYP2C9ALOX15 | |
| SCHEMBL20274161 | 0.74 | KCNH2 (0.52) | MEN1KMT2ANPC1RAB9ACYP2D6 | |
| SCHEMBL20274189 | 0.73 | L3MBTL1 (0.44) | MEN1KMT2A | |
| SCHEMBL20274113 | 0.72 | SIGMAR1 (0.39) | MEN1KMT2ACYP2D6CYP2C9ALOX15 | |
| SCHEMBL23336086 | 0.69 | FAAH (0.57) | CYP2D6CYP2C9ALOX15TSHRCYP2C19 | |
| SCHEMBL20274144 | 0.69 | MDH1 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL20274139 | 0.68 | HRH4 (0.47) | MEN1KMT2ANPC1RAB9ACYP2D6 | |
| SCHEMBL20274151 | 0.68 | FAAH (0.48) | MEN1KMT2ANPC1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |