Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274116 | 0.82 | POLB (0.54) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL20274197 | 0.82 | AKR1C3 (0.62) | MAPTLMNAHTTALDH1A1KDM4E | |
| SCHEMBL23336140 | 0.81 | AKR1C3 (0.54) | MAPTLMNAHTTALDH1A1KDM4E | |
| SCHEMBL20274112 | 0.80 | HRH3 (0.60) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL20274173 | 0.80 | AKR1C3 (0.68) | MAPTHTTALDH1A1KDM4ETSHR | |
| SCHEMBL20651220 | 0.80 | AKR1C3 (0.52) | POLBMAPTHTTGAATSHR | |
| SCHEMBL20651324 | 0.80 | AKR1C3 (0.52) | POLBMAPTLMNAALDH1A1KDM4E | |
| SCHEMBL20503419 | 0.74 | ALDH1A1 (0.46) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL945056 | 0.73 | ME2 (0.65) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL25787372 | 0.73 | ME2 (0.65) | POLBMAPTALDH1A1ME2ME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |