Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ILK | Q13418 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710713 | 0.89 | SCN4A (0.67) | SCN4ASCN9AADRB2NCF1HTR1D | |
| SCHEMBL10219273 | 0.85 | SCN4A (0.62) | SCN4ASCN9AADRB2NCF1HTR1D | |
| SCHEMBL17275047 | 0.82 | RAB9A (0.58) | SCN4ASCN9AHTR6ALDH1A1MAPT | |
| SCHEMBL20600096 | 0.79 | SCN4A (0.51) | SCN4ASCN9AADRB2HTR2CADRB1 | |
| SCHEMBL4056087 | 0.79 | NPC1 (0.57) | SCN4ASCN9AADRB2NCF1HTR6 | |
| SCHEMBL8039956 | 0.79 | AR (0.55) | SCN4ASCN9AHTR6ALDH1A1MAPT | |
| SCHEMBL23657771 | 0.79 | RAB9A (0.59) | MAPTDYRK1ANPC1RAB9APPARG | |
| SCHEMBL10219374 | 0.77 | SCN4A (0.56) | SCN4ASCN9AADRB2HTR6ALDH1A1 | |
| SCHEMBL20274141 | 0.77 | RAB9A (0.52) | MAPTDYRK1ANPC1RAB9APPARG | |
| SCHEMBL2708421 | 0.77 | DPP4 (0.49) | SCN4ASCN9AHTR6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145925-B1 | ANTHELMINTIC COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-3145925-B1 | ANTHELMINTIC COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-11-04 | — | — | EP | disclosed |
| CN-106536518-B | Anthelmintic compounds | 勃林格殷格翰动物保健美国公司 | 2020-05-12 | — | — | CN | disclosed |
| US-10463661-B2 | Anthelmintic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-11-05 | — | — | US | disclosed |
| US-10463661-B2 | Anthelmintic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180338972-A1 | ANTHELMINTIC COMPOUNDS | MERIAL INC. (US) | 2018-11-29 | — | — | US | disclosed |
| US-20170100394-A1 | ANTHELMINTIC COMPOUNDS | MERIAL INC. (US) | 2017-04-13 | — | — | US | disclosed |
| EP-3145925-A1 | ANTHELMINTIC COMPOUNDS | Merial, Inc. (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179414-A1 | ANTHELMINTIC COMPOUNDS | MERIAL, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179414-A1 | ANTHELMINTIC COMPOUNDS | MERIAL, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| US-20140357624-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2014-12-04 | — | — | US | disclosed |
| US-20140357624-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2014-12-04 | — | — | US | disclosed |
| US-8846930-B2 | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PIERRE FABRE MEDICAMENT (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8846930-B2 | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PIERRE FABRE MEDICAMENT (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8846930-B2 | Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy | PIERRE FABRE MEDICAMENT (FR) | 2014-09-30 | — | — | US | disclosed |
| EP-2643318-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | Pierre Fabre Médicament (FR) | 2013-10-02 | — | — | EP | disclosed |
| US-20130172326-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20130172326-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20130172326-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2013-07-04 | — | — | US | disclosed |
| WO-2012069503-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172326-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | KCNA4, KCNA1, KCNB1 | SCN4A 42/4885SCN9A 78/4885ADRB2 476/4885 |
| US-10463661-B2 | Anthelmintic compounds | HRH4, QTRT1, Q6ZSR9 | SCN4A 844/4885SCN9A 1170/4885ADRB2 2002/4885 |
| US-20180338972-A1 | ANTHELMINTIC COMPOUNDS | HRH4, QTRT1, Q6ZSR9 | SCN4A 844/4885SCN9A 1170/4885ADRB2 2002/4885 |
| US-20140357624-A1 | DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY | KCNA4, KCNA1, KCNB1 | SCN4A 42/4885SCN9A 78/4885ADRB2 476/4885 |
| US-20170100394-A1 | ANTHELMINTIC COMPOUNDS | HRH4, QTRT1, Q6ZSR9 | SCN4A 844/4885SCN9A 1170/4885ADRB2 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.