SCHEMBL20274685

SCHEMBL20274685

c1ccc(N(c2ccc3c4ccccc4c4ccccc4c3c2)c2ccc3c4ccccc4n(-c4ccc5ccccc5c4)c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PRSS1 P07477 1/20 0.35
HPGD P15428 1/20 0.34
HTR3A P46098 2/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR5A P47898 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
PER2 O15055 1/20 0.32
CRY1 Q16526 1/20 0.32
CRY2 Q49AN0 1/20 0.32
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 2/20 0.32
PMM2 O15305 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20274779 0.95 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL14728175 0.95 KDM4E (0.37) KDM4EATML3MBTL1F2F10
SCHEMBL18688745 0.94 KDM4E (0.38) KDM4EATML3MBTL1F2F10
SCHEMBL20274712 0.91 L3MBTL1 (0.34) KDM4EATML3MBTL1F2F10
SCHEMBL20274670 0.91 KDM4E (0.38) KDM4EATML3MBTL1F2F10
SCHEMBL14564948 0.91 KDM4E (0.42) KDM4EATML3MBTL1F2F10
SCHEMBL12559387 0.91 KDM4E (0.42) KDM4EATML3MBTL1F2F10
SCHEMBL26336151 0.91 KDM4E (0.34) KDM4EATML3MBTL1F2F10
SCHEMBL18689343 0.91 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A1CYP1A2
SCHEMBL18689336 0.90 KDM4E (0.39) KDM4EATML3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same LG CHEM, LTD. 2020-12-08 US disclosed
EP-3336077-B1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-11 EP disclosed
EP-3336077-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same EML4, OR10J3, AOC2 KDM4E 434/4885ATM 181/4885L3MBTL1 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.