SCHEMBL20276026

SCHEMBL20276026

c1ccc(-n2c3ccccc3c3ccc(-c4ccc(-c5ccc6ccc7c(-c8ccc(-c9ccccn9)cc8)ccc8ccc5c6c87)cc4)cc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ DHODH Q02127 1/20 0.37
▸ METAP2 P50579 1/20 0.35
▸ GRM5 P41594 2/20 0.34
▸ MCL1 Q07820 3/20 0.34
▸ IRAK4 Q9NWZ3 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ NPY5R Q15761 1/20 0.33
▸ CTSD P07339 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ PPP1CA P62136 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20276133 0.96 KDM4E (0.39) KDM4EATML3MBTL1DHODHMETAP2
SCHEMBL20276069 0.95 GRM5 (0.38) KDM4EATML3MBTL1DHODHMETAP2
SCHEMBL20276056 0.95 KDM4E (0.38) KDM4EATML3MBTL1DHODHMETAP2
SCHEMBL20276030 0.94 GRM5 (0.37) KDM4EATML3MBTL1DHODHMETAP2
SCHEMBL20276062 0.91 L3MBTL1 (0.41) KDM4EATML3MBTL1DHODHMETAP2
SCHEMBL12611651 0.91 MAPT (0.39) KDM4EATML3MBTL1DHODHMCL1
SCHEMBL20276098 0.90 KDM4E (0.38) KDM4EATML3MBTL1DHODHGRM5
SCHEMBL20276119 0.90 GRM5 (0.37) KDM4EATML3MBTL1DHODHGRM5
SCHEMBL20276077 0.89 MAPK14 (0.38) KDM4EATML3MBTL1METAP2GRM5
SCHEMBL20276057 0.89 GRM5 (0.36) KDM4EATML3MBTL1METAP2GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362280-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-06-14 — — US disclosed
US-11342508-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-05-24 — — US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 — — US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342508-B2 Organic light-emitting device CRY1, CRY2, NR2E3 KDM4E 2028/4885ATM 2077/4885L3MBTL1 10/4885
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 KDM4E 2028/4885ATM 2077/4885L3MBTL1 10/4885
US-11362280-B2 Organic light-emitting device CRY1, CRY2, NR2E3 KDM4E 2028/4885ATM 2077/4885L3MBTL1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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