SCHEMBL20276062

SCHEMBL20276062

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5ccc6c(-c7ccccn7)ccc7ccc4c5c76)cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ MAPK14 Q16539 1/20 0.38
▸ MAT2A P31153 1/20 0.35
▸ TSHR P16473 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ METAP2 P50579 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ GRM5 P41594 1/20 0.34
▸ NPY5R Q15761 1/20 0.34
▸ MCL1 Q07820 2/20 0.33
▸ METAP1 P53582 1/20 0.33
▸ IRAK4 Q9NWZ3 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ PPP1CA P62136 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20276077 0.96 MAPK14 (0.38) L3MBTL1KDM4EATMMAPK14MAT2A
SCHEMBL20276133 0.96 KDM4E (0.39) L3MBTL1KDM4EATMMAPK14MAT2A
SCHEMBL20276075 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMMAPK14MAT2A
SCHEMBL20276026 0.91 KDM4E (0.39) L3MBTL1KDM4EATMMAPK14MAT2A
SCHEMBL9920673 0.91 MAPK14 (0.41) L3MBTL1KDM4EATMMAPK14CYP2C19
SCHEMBL20276095 0.91 MAPK14 (0.38) L3MBTL1KDM4EATMMAPK14TSHR
SCHEMBL20276069 0.91 GRM5 (0.38) L3MBTL1KDM4EATMMAPK14TSHR
SCHEMBL20276098 0.90 KDM4E (0.38) L3MBTL1KDM4EATMMAPK14MAT2A
SCHEMBL9921061 0.90 MAPK14 (0.41) L3MBTL1KDM4EATMMAPK14GRM5
SCHEMBL20276030 0.90 GRM5 (0.37) L3MBTL1KDM4EATMMAPK14TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362280-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-06-14 — — US disclosed
US-11342508-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-05-24 — — US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 — — US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342508-B2 Organic light-emitting device CRY1, CRY2, NR2E3 L3MBTL1 10/4885KDM4E 2028/4885ATM 2077/4885
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 L3MBTL1 10/4885KDM4E 2028/4885ATM 2077/4885
US-11362280-B2 Organic light-emitting device CRY1, CRY2, NR2E3 L3MBTL1 10/4885KDM4E 2028/4885ATM 2077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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