Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027602 | 1.00 | ECE1 (0.35) | ECE1CCR1CCR8KDM4EALOX15 | |
| SCHEMBL2026657 | 0.89 | KDM4E (0.42) | KDM4EALOX15TDP1TSHRACMSD | |
| SCHEMBL2026659 | 0.89 | KDM4E (0.42) | KDM4EALOX15TDP1TSHRACMSD | |
| SCHEMBL3708925 | 0.79 | P2RX7 (0.50) | CCR1CCR8KDM4EHSP90AA1 | |
| SCHEMBL3708926 | 0.79 | P2RX7 (0.50) | CCR1CCR8KDM4EHSP90AA1 | |
| SCHEMBL1770237 | 0.73 | F10 (0.39) | ECE1CCR1CCR8KDM4EALOX15 | |
| SCHEMBL9792815 | 0.73 | CCR1 (0.37) | ECE1CCR1CCR8KDM4EALOX15 | |
| SCHEMBL9792961 | 0.73 | PIM1 (0.50) | ECE1KDM4EALOX15TDP1TSHR | |
| Hydrochloric Acid SCHEMBL9792874 | 0.71 | BLM (0.39) | ECE1CCR1CCR8HTTSCN9A | |
| SCHEMBL834329 | 0.70 | KDM4E (0.54) | KDM4ETDP1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516378-B1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | UNIV READING (GB) | 2014-01-22 | — | — | EP | disclosed |
| EP-2516378-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | The University of Reading (GB) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2012-10-18 | — | — | US | disclosed |
| WO-2011077081-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | ENO1, DIAPH1, DBN1 | ECE1 609/4885CCR1 2389/4885CCR8 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.