Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026659 | 1.00 | KDM4E (0.42) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL2027604 | 0.89 | ECE1 (0.35) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL2027602 | 0.89 | ECE1 (0.35) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL3708925 | 0.85 | P2RX7 (0.50) | KDM4EMEN1KMT2A | |
| SCHEMBL3708926 | 0.85 | P2RX7 (0.50) | KDM4EMEN1KMT2A | |
| SCHEMBL12560610 | 0.75 | KDM4E (0.54) | KDM4ETDP1KMT2A | |
| SCHEMBL834329 | 0.75 | KDM4E (0.54) | KDM4ETDP1KMT2A | |
| SCHEMBL1428592 | 0.75 | KDM4E (0.54) | KDM4ETDP1KMT2A | |
| SCHEMBL28971368 | 0.73 | KDM4E (0.41) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL3373490 | 0.72 | PIM1 (0.49) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516378-B1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | UNIV READING (GB) | 2014-01-22 | — | — | EP | disclosed |
| EP-2516378-B1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | UNIV READING (GB) | 2014-01-22 | — | — | EP | disclosed |
| EP-2516378-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | The University of Reading (GB) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2012-10-18 | — | — | US | disclosed |
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2012-10-18 | — | — | US | disclosed |
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2012-10-18 | — | — | US | disclosed |
| WO-2011077081-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011077081-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | THE UNIVERSITY OF READING (GB) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264935-A1 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION | ENO1, DIAPH1, DBN1 | KDM4E 672/4885ALOX15 1299/4885TSHR 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.