Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | WNT3A | P56704 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043065 | 0.82 | GPR3 (0.35) | GPR3CTNNB1WNT3AHDAC4NOTUM | |
| SCHEMBL848935 | 0.81 | ALOX5 (0.38) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL2346478 | 0.80 | CTNNB1 (0.38) | GPR3CTNNB1WNT3AHDAC4PIK3CA | |
| SCHEMBL6990050 | 0.77 | ALOX5 (0.35) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL2708355 | 0.77 | ALOX5 (0.35) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL24181276 | 0.77 | ALOX5 (0.35) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL8764608 | 0.77 | ALOX5 (0.35) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL19492665 | 0.77 | ALOX5 (0.35) | GPR3CTNNB1WNT3AALOX5ABCG2 | |
| SCHEMBL7489327 | 0.75 | KIF11 (0.55) | GPR3CTNNB1WNT3AALOX5HDAC4 | |
| SCHEMBL30185992 | 0.73 | ALOX5 (0.41) | ALOX5ABCG2ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594261-B2 | Use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases | SHANGHAI EAST HOSPITAL (EAST HOSPITAL, TONGJI UNIVERSITY SCHOOL OF MEDICINE) (CN) | 2026-04-07 | — | — | US | claimed |
| EP-4043017-B1 | CANCER TREATMENT USING COMBINATIONS OF ERK AND RAF INHIBITORS | BIOMED VALLEY DISCOVERIES INC (US) | 2026-01-28 | — | — | EP | claimed |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| US-20250122218-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2025-04-17 | — | — | US | claimed |
| EP-4511018-A1 | 4-CHROMONE DERIVATIVES AS N-POLYMERASE INHIBITORS FOR USE IN THE TREATMENT PLATINUM RESISTANT METASTATIC NEOPLASM | Fondazione Istituto Italiano di Tecnologia (IT) | 2025-02-26 | — | — | EP | claimed |
| EP-4476230-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2024-12-18 | — | — | EP | claimed |
| EP-3082423-B1 | CANCER TREATMENTS USING COMBINATIONS OF CDK AND ERK INHIBITORS | BIOMED VALLEY DISCOVERIES INC (US) | 2024-12-11 | — | — | EP | claimed |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2024-08-27 | — | — | US | claimed |
| WO-2024128305-A1 | 2-AZABICYCLO[3.1.1]HEPTANE COMPOUND | 第一三共株式会社 | 2024-06-20 | — | — | WO | claimed |
| CN-117813077-A | Composition and method for producing the same | 西姆莱斯股份公司 | 2024-04-02 | — | — | CN | claimed |
| US-5432290-A | Fluorination | RHONE-POULENC CHIMIE (FR) | 1995-07-11 | — | — | US | claimed |
| US-5420301-A | Process for the preparation of substituted difluorobenzo-1,3-dioxoles | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | claimed |
| EP-0333661-B1 | Process for the preparation of a pyrole derivative | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | claimed |
| US-5281718-A | Reacting in one pot reaction 2,2-difluorobenzodioxole with an organometal compound or metal to form 4-metallo-2,2-difluorobenzodioxole, reacting with unsaturated nitrile, then with isocyanide | CIBA-GEIGY CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| EP-0505742-A2 | Process for the production of 4-cyanopyrrole compounds substituted at the 3-position | BAYER AG (DE) | 1992-09-30 | — | — | EP | claimed |
| EP-0333661-A2 | Process for the preparation of a pyrole derivative | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | claimed |
| EP-0333658-A2 | Process for the preparation of substituted difluorbenzo-1,3-dioxoles | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | claimed |
| US-4791124-A | INSECTICIDES, MITICIDES, NEMATOCIDES | FMC CORPORATION (US) | 1988-12-13 | — | — | US | claimed |
| CN-87103235-A | The photosensitive azole pesticides | — | 1988-06-08 | — | — | CN | claimed |
| WO-1987006429-A1 | PHOTOACTIVE AZOLE PESTICIDES | FMC CORPORATION (US) | 1987-11-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | GPR3 13/4885CTNNB1 3832/4885WNT3A 3138/4885 |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC1 | GPR3 447/4885CTNNB1 192/4885WNT3A 311/4885 |
| US-12594261-B2 | Use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases | TNNT2, TNNI3, CCNO | GPR3 483/4885CTNNB1 210/4885WNT3A 353/4885 |
| US-20250122218-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | GPR3 982/4885CTNNB1 3162/4885WNT3A 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.