Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378390 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL27300740 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL12308089 | 0.92 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL19976435 | 0.91 | TSHR (0.62) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL19976470 | 0.91 | TSHR (0.59) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL10148601 | 0.91 | TSHR (0.59) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL19976436 | 0.91 | TSHR (0.59) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL18392677 | 0.89 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL3136372 | 0.87 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ACYP2D6 | |
| SCHEMBL20870237 | 0.87 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708387-B2 | Hexose derivatives, preparation and uses thereof | FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2023-07-25 | — | — | US | disclosed |
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-02-16 | — | — | US | disclosed |
| US-20190216895-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2019-07-18 | — | — | US | disclosed |
| US-20180170955-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | UNIVERSIDADE NOVA DE LISBOA (PT) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | DDOST, SI, CD4 | TSHR 3529/4885ALDH1A1 3748/4885LMNA 4672/4885 |
| US-20180170955-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | HK1, SLC5A1, HK2 | TSHR 1293/4885ALDH1A1 857/4885LMNA 3078/4885 |
| US-20190216895-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | GFRA2, GFRA1, NGF | TSHR 2965/4885ALDH1A1 133/4885LMNA 3556/4885 |
| US-11708387-B2 | Hexose derivatives, preparation and uses thereof | HK1, SLC5A1, HK2 | TSHR 1293/4885ALDH1A1 857/4885LMNA 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.