Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27846898 | 0.83 | TAAR1 (0.39) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL28162095 | 0.81 | FFAR1 (0.45) | CA2CA1LMNA | |
| SCHEMBL855255 | 0.80 | LOXL2 (0.41) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL3643384 | 0.80 | PPARG (0.41) | CA2CA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27756025 | 0.80 | PTGS2 (0.34) | CA2CA1CYP3A4CYP1A2CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL23885016 | 0.79 | LOXL2 (0.40) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL27364974 | 0.79 | CYP3A4 (0.41) | CA2CA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7249558 | 0.77 | CYP4F2 (0.55) | — | |
| SCHEMBL5212646 | 0.77 | ANPEP (0.43) | CA2CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8127986 | 0.77 | CYP3A4 (0.38) | CYP3A4CYP1A2CYP2D6CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176277-B1 | NUCLEOTIDES AND APTAMERS CONTAINING BORONIC ACID GROUPS HAVING BIASED BINDING TO GLYCOSYLATED PROTEINS, AND USES THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2016-02-24 | — | — | EP | disclosed |
| US-9096856-B2 | Nucleotides and aptamers containing boronic acid groups having biased binding to glycosylated proteins, and uses thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130184160-A1 | NUCLEOTIDES AND APTAMERS CONTAINING BORONIC ACID GROUPS HAVING BIASED BINDING TO GLYCOSYLATED PROTEINS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-07-18 | — | — | US | disclosed |
| US-20110144187-A1 | APTAMER INHIBITION OF THROMBUS FORMATION | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184160-A1 | NUCLEOTIDES AND APTAMERS CONTAINING BORONIC ACID GROUPS HAVING BIASED BINDING TO GLYCOSYLATED PROTEINS, AND USES THEREOF | TENT4A, PABPC4, NUDT21 | S1PR1 2714/4885S1PR2 2941/4885S1PR3 3033/4885 |
| US-20110144187-A1 | APTAMER INHIBITION OF THROMBUS FORMATION | FGB, F13B, GP6 | S1PR1 4304/4885S1PR2 4456/4885S1PR3 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.