Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
| ▸ | CA7 | P43166 | 1/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576461 | 0.94 | CA1 (0.67) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL18546011 | 0.90 | CA1 (0.66) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6491441 | 0.87 | CA1 (0.71) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6340653 | 0.87 | CA1 (0.63) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL3453018 | 0.87 | CA1 (0.67) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL29765433 | 0.86 | CA1 (0.65) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL259393 | 0.84 | NPC1 (0.67) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL16248330 | 0.84 | HTR1A (0.63) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL2134679 | 0.84 | RAB9A (0.67) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL7749816 | 0.83 | CA1 (0.58) | CA1CA2CA5ACA7CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377061-A1 | MIRABEGRON FOR THE TREATMENT OF RETINAL DISEASES | Sorbonne Université (FR) | 2018-09-26 | — | — | EP | disclosed |
| EP-2507212-B1 | PROCESS FOR PREPARING METHYL PHENIDATE HYDROCHLORIDE | HARMAN FINOCHEM LTD (IN) | 2014-04-16 | — | — | EP | disclosed |
| EP-2507212-A1 | PROCESS FOR PREPARING METHYL PHENIDATE HYDROCHLORIDE | Harman Finochem Limited (IN) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067783-A1 | PROCESS FOR PREPARING METHYL PHENIDATE HYDROCHLORIDE | HARMAN FINOCHEM LIMITED (IN) | 2011-06-09 | — | — | WO | disclosed |
| EP-1224163-B1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2005-03-30 | — | — | EP | disclosed |
| CN-1136193-C | Imide derivatives or salts thereof | ֮����ҩ��ʽ���� | 2004-01-28 | — | — | CN | disclosed |
| US-6548522-B1 | N-substituted 2,2-diphenylacetamide or N-substituted 2-phenyl-2-pyridinylacetamide | HOFFMANN-LA ROCHE INC. | 2003-04-15 | — | — | US | disclosed |
| EP-1224163-A1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027070-A1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-19 | — | — | WO | disclosed |
| CN-1218045-A | Imide derivatives or salts thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1999-06-02 | — | — | CN | disclosed |
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4008326-A | INCREASING PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |