SCHEMBL2028435

SCHEMBL2028435

CCC(CC)(O[O])C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717671 0.85 DGAT1 (0.34) DGAT1
SCHEMBL20210944 0.82 DGAT1 (0.41) DGAT1CA12CA1CA7CA14
SCHEMBL26815958 0.80 DGAT1 (0.40) DGAT1CA12CA1CA7CA14
SCHEMBL15082441 0.73 DGAT1 (0.46) DGAT1CA12CA1CA7CA14
SCHEMBL47394 0.73 DGAT1 (0.46) DGAT1CA12CA1CA7CA14
SCHEMBL28004334 0.73 DGAT1 (0.46) DGAT1CA12CA1CA7CA14
SCHEMBL15859564 0.72 DGAT1 (0.34) DGAT1
SCHEMBL15779606 0.71 DGAT1 (0.44) DGAT1CA12CA1CA7CA14
SCHEMBL26815955 0.71 DGAT1 (0.44) DGAT1CA12CA1CA7CA14
SCHEMBL10052299 0.71 DGAT1 (0.44) DGAT1CA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3065944-B1 MODIFICATION OF POLYAMIDES ARKEMA INC (US) 2022-01-19 EP disclosed
US-10787604-B2 Colored organic peroxide compositions and methods for breaking fluids ARKEMA INC. (US) 2020-09-29 US disclosed
US-10358559-B2 Colored organic peroxide compositions ARKEMA INC. (US) 2019-07-23 US disclosed
US-10294414-B2 Compositions and methods for breaking hydraulic fracturing fluids ARKEMA INC. (US) 2019-05-21 US disclosed
US-10138413-B2 Promoters for peroxides in aqueous treatment fluids ARKEMA INC. (US) 2018-11-27 US disclosed
US-20180079952-A1 COLORED ORGANIC PEROXIDE COMPOSITIONS AND METHODS FOR BREAKING HYDRAULIC FRACTURING FLUIDS ARKEMA INC. 2018-03-22 US disclosed
US-20180079908-A1 COLORED ORGANIC PEROXIDE COMPOSITIONS ARKEMA INC. 2018-03-22 US disclosed
EP-3277772-A1 COLORED ORGANIC PEROXIDE COMPOSITIONS AND METHODS FOR BREAKING HYDRAULIC FRACTURING FLUIDS Arkema Inc. (US) 2018-02-07 EP disclosed
EP-3274323-A1 COLORED ORGANIC PEROXIDE COMPOSITIONS Arkema, Inc. (US) 2018-01-31 EP disclosed
US-20170275528-A1 COMPOSITIONS AND METHODS FOR BREAKING HYDRAULIC FRACTURING FLUIDS ARKEMA INC. 2017-09-28 US disclosed
WO-2005110954-A1 METHOD FOR RECOVERING TRANS-1,2-DICHLOROETHENE PPG INDUSTRIES OHIO, INC. (US) 2005-11-24 WO disclosed
US-20050245775-A1 Method for recovering trans-1,2-dichloroethene EAGLE US 2 LLC 2005-11-03 US disclosed
US-20040030203-A1 Method of stabilizing trichloroethane during production PPG INDUSTRIES OHIO, INC. 2004-02-12 US disclosed
US-6150573-A Concurrent production of trichloroethane isomers PPG INDUSTRIES OHIO, INC. (US) 2000-11-21 US disclosed
US-5382727-A Free radical chlorination of 1,1-dichloroethane PPG INDUSTRIES, INC. (US) 1995-01-17 US disclosed
US-5315052-A Concurrent production of trichloroethane isomers PPG INDUSTRIES, INC. (US) 1994-05-24 US disclosed
US-5298646-A Introducing molecular chlorine to stripping zone, contacting ethyl chloroformate in rectifying zone, condensation, refluxing, removal of gaseous phase PPG INDUSTRIES, INC. (US) 1994-03-29 US disclosed
US-5051536-A Using a free radical catalyst to form cis-, trans-isomers PPG INDUSTRIES, INC. (US) 1991-09-24 US disclosed
WO-1991002708-A1 METHOD FOR ISOMERIZING 1,2-DICHLOROETHENE PPG INDUSTRIES, INC. (US) 1991-03-07 WO disclosed
US-4189517-A UNSATURATED POLYESTER, SATURATED POLYESTER, DIISOCYANATE, CROSSLINKING POLYOL, POLYVINYL ACETATE THE GENERAL TIRE & RUBBER COMPANY (US) 1980-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040030203-A1 Method of stabilizing trichloroethane during production TTPA, CBR1, TCEA1 DGAT1 150/4885CA12 3265/4885CA1 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.