Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720456 | 0.77 | TSHR (0.48) | NPC1RAB9ATSHRMAPTIDO1 | |
| SCHEMBL22529366 | 0.74 | NPC1 (0.46) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL9517958 | 0.72 | LMNA (0.41) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL156310 | 0.72 | TSHR (0.48) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL6175561 | 0.72 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL3359456 | 0.72 | MAPK1 (0.51) | NPC1RAB9AMEN1KMT2AMAPT | |
| Ammonia Solution, Strong SCHEMBL11782377 | 0.71 | TSHR (0.46) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL27502228 | 0.71 | LMNA (0.39) | NPC1RAB9ATSHRMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27855921 | 0.71 | LMNA (0.39) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL27916932 | 0.71 | TSHR (0.46) | NPC1RAB9ATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTHCARE AG (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20110170075-A1 | DEVICE FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2011-07-14 | — | — | US | disclosed |
| EP-2332645-A1 | Apparatus for chemical and biochemical reactions using photo-generated reagents | THE UNIVERSITY OF HOUSTON (US) | 2011-06-15 | — | — | EP | disclosed |
| US-7838466-B2 | Device for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-11-23 | — | — | US | disclosed |
| US-20100028939-A1 | Use of Galactose Oxidase for Selective Chemical Conjugation of Protractor Molecules to Proteins of Therapeutic Interest | NOVO NORDISK HEALTHCARE A/G (CH) | 2010-02-04 | — | — | US | disclosed |
| US-7544638-B2 | Device for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-06-09 | — | — | US | disclosed |
| US-7491680-B2 | Device for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080318806-A1 | DEVICE FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080248971-A1 | METHOD FOR PROVIDING MICROARRAYS | INVITROGEN CORPORATION (US) | 2008-10-09 | — | — | US | disclosed |
| US-20060198819-A1 | Use of galactose oxidase for selective chemical conjugation of protractor molecules to proteins of therapeutic interest | NOVO NORDISK HEALTHCARE A/G (CH) | 2006-09-07 | — | — | US | disclosed |
| US-20040035690-A1 | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2004-02-26 | — | — | US | disclosed |
| US-20040023368-A1 | Apparatus for light controlled parallel synthesis of molecular sequence arrays on solid surfaces | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2004-02-05 | — | — | US | disclosed |
| US-20030186427-A1 | Apparatus for selectively converting photogenerated reagent precursors to photogenerated reagents associated with parallel synthesis of molecular sequence arrays on solid surfaces | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2003-10-02 | — | — | US | disclosed |
| US-20030143131-A1 | For parallel synthesis of molecular sequence arrays on solid surfaces | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2003-07-31 | — | — | US | disclosed |
| EP-1054726-B1 | APPARATUS FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | UNIV HOUSTON OFFICE OF TECHNOL (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-1258288-A2 | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | THE UNIVERSITY OF HOUSTON (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6426184-B1 | MAKING MULTIMERS SUCH AS DNA OR PEPTIDES IN CHEMICAL REACTOR BY SOLUTION-BASED PHOTOCHEMICAL REACTIONS INVOLVING REAGENTS GENERATED IN SITU BY IRRADIATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-30 | — | — | US | disclosed |
| US-20020081582-A1 | Making multimers such as DNA or peptides in chemical reactor by solution-based photochemical reactions involving reagents generated in situ by irradiation | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2002-06-27 | — | — | US | disclosed |
| EP-1054726-A2 | METHOD AND APPARATUS FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | THE UNIVERSITY OF HOUSTON (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041007-A2 | METHOD AND APPARATUS FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | UNIVERSITY OF HOUSTON (US) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060198819-A1 | Use of galactose oxidase for selective chemical conjugation of protractor molecules to proteins of therapeutic interest | GALE, GALNT2, GALNT1 | NPC1 4364/4885RAB9A 2751/4885TSHR 1226/4885 |
| US-20040035690-A1 | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | PPOX, LIG4, AOX1 | NPC1 4768/4885RAB9A 4376/4885TSHR 1371/4885 |
| US-20140274903-A1 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | GALE, GALNT2, GALNT1 | NPC1 4364/4885RAB9A 2751/4885TSHR 1226/4885 |
| US-20100028939-A1 | Use of Galactose Oxidase for Selective Chemical Conjugation of Protractor Molecules to Proteins of Therapeutic Interest | GALE, GALNT2, GALNT1 | NPC1 4364/4885RAB9A 2751/4885TSHR 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.