Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535542 | 0.76 | CYP19A1 (0.58) | NPC1RAB9ACYP19A1KMT2ACA1 | |
| SCHEMBL28926322 | 0.76 | CA2 (0.59) | NPC1RAB9AKMT2ACA1CA2 | |
| SCHEMBL30586133 | 0.75 | AR (0.62) | NPC1RAB9ACYP19A1KMT2ACA1 | |
| SCHEMBL4421032 | 0.75 | AR (0.62) | NPC1RAB9ACYP19A1KMT2ACA1 | |
| Methane SCHEMBL7670761 | 0.74 | CA2 (0.57) | NPC1RAB9AKMT2ACA1CA2 | |
| SCHEMBL2028618 | 0.74 | NPC1 (0.50) | NPC1RAB9AKMT2ACA1CA2 | |
| SCHEMBL7670765 | 0.74 | NPC1 (0.51) | NPC1RAB9ACYP19A1KMT2ACA1 | |
| SCHEMBL217534 | 0.73 | CA2 (0.55) | NPC1RAB9ACYP19A1KMT2ACA1 | |
| SCHEMBL10837819 | 0.73 | KMT2A (0.64) | NPC1RAB9AKMT2ACA1CA2 | |
| SCHEMBL4349161 | 0.72 | AR (0.64) | CYP19A1KMT2ACA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300926-A1 | NEW BETA-LACTAMASE INHIBITORS TARGETING GRAM NEGATIVE BACTERIA | UNIVERSITÉ PARIS CITÉ (FR) | 2021-09-30 | — | — | US | disclosed |
| EP-3728258-A1 | NEW ANTIBIOTICS TARGETING MYCOBACTERIA | Centre National de la Recherche Scientifique (FR) | 2020-10-28 | — | — | EP | disclosed |
| EP-3728259-A1 | NEW BETA-LACTAMASE INHIBITORS TARGETING GRAM NEGATIVE BACTERIA | Centre National de la Recherche Scientifique (FR) | 2020-10-28 | — | — | EP | disclosed |
| US-20200325139-A1 | NEW ANTIBIOTICS TARGETING MYCOBACTERIA | UNIVERSITÉ PARIS CITÉ (FR) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325139-A1 | NEW ANTIBIOTICS TARGETING MYCOBACTERIA | MAGT1, RPN2, MAFG | NPC1 243/4885RAB9A 1111/4885CYP19A1 4798/4885 |
| US-20210300926-A1 | NEW BETA-LACTAMASE INHIBITORS TARGETING GRAM NEGATIVE BACTERIA | LCT, MGAM, PGLS | NPC1 2010/4885RAB9A 725/4885CYP19A1 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.