O-Xylene

O-Xylene

SCHEMBL2028627

C=CC[Na].Cc1ccccc1C

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.53
TSHR P16473 2/20 0.53
ALDH1A1 P00352 6/20 0.39
CYP2A6 P11509 2/20 0.39
KDM4E B2RXH2 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 1/20 0.36
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL11054463 0.81 TSHR (0.56) ACHETSHRALDH1A1CYP2A6CA1
Naphthalene SCHEMBL965746 0.80 CYP2A6 (0.50) ACHETSHRALDH1A1CYP2A6KDM4E
O-Xylene SCHEMBL7624343 0.77 TSHR (0.67) ACHETSHRALDH1A1CYP2A6CA1
O-Xylene SCHEMBL3673577 0.77 TSHR (0.67) ACHETSHRALDH1A1CYP2A6CA1
O-Xylene SCHEMBL2065413 0.75 TSHR (0.48) ACHETSHRALDH1A1KDM4EMAPT
O-Xylene SCHEMBL4088288 0.75 PAM (0.44) ACHETSHRALDH1A1HTTCYP3A4
O-Xylene SCHEMBL16048907 0.75 TSHR (0.62) ACHETSHRALDH1A1CYP2A6CA1
O-Xylene SCHEMBL8642954 0.75 TSHR (0.62) ACHETSHRALDH1A1CYP2A6CA1
O-Xylene SCHEMBL16892914 0.75 TSHR (0.62) ACHETSHRALDH1A1CYP2A6CA1
Benzene SCHEMBL3079882 0.73 TSHR (0.31) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964745-B2 Method of making a synthetic alkylaryl sulfonate CHEVRON ORONITE COMPANY LLC (US) 2011-06-21 US disclosed
EP-2231593-A1 A METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE Chevron Oronite Company LLC (US) 2010-09-29 EP disclosed
US-7598414-B2 Method of making a synthetic alkylaryl sulfonate CHEVRON ORONITE COMPANY LLC (US) 2009-10-06 US disclosed
US-20090209778-A1 METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE CHEVRON ORONITE COMPANY LLC 2009-08-20 US disclosed
WO-2009085964-A1 A METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE CHEVRON ORONITE COMPANY LLC (US) 2009-07-09 WO disclosed
US-20090163669-A1 METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE Chevron Oronite LLC 2009-06-25 US disclosed
WO-2009017497-A2 A METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE CHEVRON ORONITE COMPANY LLC (US) 2009-02-05 WO disclosed
US-20070282125-A1 Method of making a synthetic alkylaryl sulfonate CHEVRON ORONITE COMPANY LLC 2007-12-06 US disclosed