O-Xylene

O-Xylene

SCHEMBL4088288

C=CCC(=O)O.Cc1ccccc1C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 2/20 0.42
ACHE P22303 1/20 0.42
ALDH1A1 P00352 2/20 0.40
CYP2C19 P33261 1/20 0.40
ITGB3 P05106 2/20 0.40
ITGAV P06756 2/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ITGB1 P05556 1/20 0.40
ITGA5 P08648 1/20 0.40
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
AKT1 P31749 1/20 0.39
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodobenzene SCHEMBL28964206 0.83 PAM (0.44) PAMKMT2ATSHRALDH1A1CYP2C19
Biphenyl SCHEMBL11045970 0.83 LMNA (0.48) PAMKMT2ASMN1; SMN2TSHRALDH1A1
SCHEMBL27890700 0.82 TRPA1 (0.57) KMT2AALDH1A1L3MBTL1GAACYP3A4
Benzene SCHEMBL11645295 0.82 ALDH1A1 (0.47) PAMKMT2AMEN1TSHRALDH1A1
Phenol SCHEMBL17183829 0.81 CA2 (0.48) PAMTSHRALDH1A1CYP2C19AKT1
Benzoic Acid SCHEMBL11147183 0.79 TSHR (0.58) PAMKMT2AMEN1SMN1; SMN2TSHR
Phthalic Acid SCHEMBL35170 0.79 ALDH1A1 (0.58) PAMKMT2ASMN1; SMN2ALDH1A1CYP3A4
SCHEMBL10781610 0.79 PAM (0.44) PAMKMT2AMEN1TSHRALDH1A1
Styrene SCHEMBL1904235 0.79 ALDH1A1 (0.58) PAMSMN1; SMN2TSHRALDH1A1CYP2C19
Aniline SCHEMBL30887654 0.79 TSHR (0.46) PAMTSHRALDH1A1CYP2C19AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153881-A1 ANTI-NOISE SHIM Omniafibre S.r.l. (IT) 2023-03-29 EP claimed
WO-2021234533-A1 ANTI-NOISE SHIM OMINIAFIBRE S.R.L. (IT) 2021-11-25 WO claimed
WO-2014182170-A1 A METHOD OF APPLYING ADHESIVE SABA DINXPERLO B.V. (NL) 2014-11-13 WO claimed
EP-2054769-A1 UV-DOSIS INDICATORS Ciba Holding Inc. (CH) 2009-05-06 EP disclosed
WO-2008022952-A1 UV-DOSIS INDICATORS CIBA HOLDING INC. (CH) 2008-02-28 WO disclosed