Naphthalene

Naphthalene

SCHEMBL965746

C=CC[Na].c1ccc2ccccc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.50
ALOX12 P18054 2/20 0.50
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
EGFR P00533 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
JAK1 P23458 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 3/20 0.36
ACHE P22303 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL7042461 0.85 ALDH1A1 (0.38) CYP2A6ALOX12ALDH1A1KDM4ECYP3A4
Naphthalene SCHEMBL23527405 0.81 ALOX12 (0.50) CYP2A6ALOX12ALDH1A1KDM4ECYP3A4
O-Xylene SCHEMBL2028627 0.80 ACHE (0.53) CYP2A6ALDH1A1KDM4ECYP3A4TDP1
Benzene SCHEMBL3079882 0.79 TSHR (0.31) ALDH1A1TSHR
Phenol SCHEMBL6536081 0.78 CA12 (0.55) ALDH1A1TDP1MEN1KMT2ATSHR
Naphthalene SCHEMBL56790 0.76 CYP2A6 (0.61) CYP2A6ALOX12ALDH1A1KDM4ECYP3A4
SCHEMBL326295 0.75
Naphthalene SCHEMBL10831150 0.75 ALOX12 (0.42) CYP2A6ALOX12ALDH1A1KDM4ETDP1
Naphthalene SCHEMBL8370666 0.75 CYP3A4 (0.43) CYP2A6ALOX12ALDH1A1KDM4ECYP3A4
Naphthalene SCHEMBL10706759 0.73 CYP2A6 (0.57) CYP2A6ALOX12ALDH1A1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109486561-A The agent of conduction oil on-line cleaning and conduction oil on-line cleaning method 上海久星导热油股份有限公司 2019-03-19 CN claimed
US-20080020239-A1 Substrate For Magnetic Recording Medium, Magnetic Recording Medium, And Magnetic Recording And Reproducing Device SHOWA DENKO K.K. (JP) 2008-01-24 US claimed
WO-2005119659-A1 SUBSTRATE FOR MAGNETIC RECORDING MEDIUM, MAGNETIC RECORDING MEDIUM, AND MANGETIC RECORDING AND REPRODUCING DEVICE SHOWA DENKO K.K. (JP) 2005-12-15 WO claimed
US-5132038-A Anionic surfactants containing sulfonate diphenyl ether MACDERMID, INCORPORATED (US) 1992-07-21 US claimed
CN-109294352-A A kind of automatically cleaning water-based fluorocarbon building coating and preparation method 成都新柯力化工科技有限公司 2019-02-01 CN disclosed
US-20180265808-A1 CLEANING COMPOSITION AND METHOD OF FORMING THE SAME BASF CORPORATION 2018-09-20 US disclosed
EP-3247782-A1 CLEANING COMPOSITION AND METHOD OF FORMING THE SAME BASF SE (DE) 2017-11-29 EP disclosed
CN-103561578-B Stable biocontrol water dispersible granules 先正达参股股份有限公司 2016-10-12 CN disclosed
WO-2016118728-A1 CLEANING COMPOSITION AND METHOD OF FORMING THE SAME BASF SE (DE) 2016-07-28 WO disclosed
EP-2287357-B1 Preparing substrates containing polymers for metallization ROHM & HAAS ELECT MAT (US) 2016-04-13 EP disclosed
EP-1153901-B1 Composition for increasing the vegetable nutritional quality and the use thereof CONSORZIO PATATA ITALIANA DI QUALIT SOCIET CONSORTILE A RESPONSABILIT LIMITATA (IT) 2015-07-08 EP disclosed
US-20140336094-A1 CLEANING COMPOSITION AND METHOD OF FORMING THE SAME BASF CORPORATION 2014-11-13 US disclosed
US-4490194-A OXYGEN SUPPLYING SALT AND CRYSTAL GROWTH INHIBITOR IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-25 US disclosed
US-4489108-A Photochromic assembly and manufacture of this assembly CIBA-GEIGY AG (CH) 1984-12-18 US disclosed
US-4444939-A LATEX, GLASS BEADS CIBA-GEIGY AG (CH) 1984-04-24 US disclosed
EP-0099695-A2 Emulsion explosive composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-01 EP disclosed
EP-0018085-B1 EXPLOSIVE COMPOSITIONS BASED ON TIME-STABLE COLLOIDAL DISPERSIONS AND A PROCESS FOR THE PREPARATION THEREOF C.I.L. Inc. (CA) 1982-12-29 EP disclosed
US-4357184-A Explosive compositions based on time-stable colloidal dispersions C-I-L INC. (CA) 1982-11-02 US disclosed
EP-0018085-A2 Explosive compositions based on time-stable colloidal dispersions and a process for the preparation thereof C.I.L. Inc. (CA) 1980-10-29 EP disclosed
US-3948822-A DISODIUM-N-OCTADECYL SULFOSUCCINAMATE, SODIUM FORMALDEHYDE SULFOXYLATE CHEMISCHE INDUSTRIE AKU-GOODRICH B.V. (NL) 1976-04-06 US disclosed