SCHEMBL2028829

SCHEMBL2028829

C=Cc1ccccc1COC(=O)C(=C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ELANE P08246 1/20 0.36
ALDH1A1 P00352 4/20 0.35
POLB P06746 3/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 4/20 0.33
LMNA P02545 2/20 0.33
CYP3A4 P08684 1/20 0.33
BACE1 P56817 1/20 0.33
PLIN1 O60240 1/20 0.33
PLIN5 Q00G26 1/20 0.33
ABHD5 Q8WTS1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RAB9A P51151 2/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61037 0.85 ALDH1A1 (0.50) ALDH1A1POLBKMT2AMAPTLMNA
SCHEMBL4202389 0.85 TSHR (0.44) TSHRELANEALDH1A1POLBAPEX1
SCHEMBL29577269 0.85 TSHR (0.44) TSHRELANEALDH1A1POLBAPEX1
SCHEMBL4421001 0.82 TSHR (0.39) TSHRELANEALDH1A1POLBAPEX1
SCHEMBL641784 0.82 THRB (0.49) TSHRELANEALDH1A1POLBAPEX1
Trimethylammonium SCHEMBL23711255 0.81 ALDH1A1 (0.46) ALDH1A1POLBKMT2AMAPTLMNA
Alcohol SCHEMBL11693989 0.81 ALDH1A1 (0.46) ALDH1A1POLBTHRBKMT2AMEN1
SCHEMBL12804388 0.81 TSHR (0.36) TSHRELANEALDH1A1POLBAPEX1
SCHEMBL28921993 0.81 MAPT (0.49) TSHRALDH1A1POLBTDP1THRB
SCHEMBL1372181 0.80 THRB (0.42) TSHRELANEALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524557-B1 Ocular lens material MENICON CO LTD (JP) 1996-01-17 EP claimed
US-5250583-A Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer MENICON CO., LTD. (JP) 1993-10-05 US claimed
EP-0524557-A2 Ocular lens material Menicon Co., Ltd. (JP) 1993-01-27 EP claimed
CN-116622168-A Low-surface free energy culture dish and preparation method thereof 深圳市碳源生物科技有限公司 2023-08-22 CN disclosed
CN-114806869-A Culture dish and application thereof in preparing cell film 深圳市碳源生物科技有限公司 2022-07-29 CN disclosed
CN-107921753-B Composite article comprising a multilayer barrier component and method of making the same 3M创新有限公司 2020-09-11 CN disclosed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 CN disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 US disclosed
US-5661194-A POLYMER FROM MONOMERS OF (METH)ACRYLAMIDE TYPE MONOMER, FLUOROALKYL (SILICON-CONTAINING ALKYL) FUMARATE MONOMER, AND CROSSLINKING MONOMER MENICON CO., LTD. (JP) 1997-08-26 US disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
EP-0722110-A2 Water absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-07-17 EP disclosed
EP-0524557-B1 Ocular lens material MENICON CO LTD (JP) 1996-01-17 EP disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
US-5250583-A Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer MENICON CO., LTD. (JP) 1993-10-05 US disclosed
EP-0524557-A2 Ocular lens material Menicon Co., Ltd. (JP) 1993-01-27 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 TSHR 4718/4885ELANE 722/4885ALDH1A1 2838/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 TSHR 4718/4885ELANE 722/4885ALDH1A1 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.