Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4200777 | 1.00 | ALDH1A1 (0.31) | ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL2023162 | 0.88 | PKM (0.31) | PKMSMN1; SMN2 | |
| SCHEMBL2326667 | 0.88 | PKM (0.31) | PKMSMN1; SMN2 | |
| SCHEMBL4412656 | 0.86 | PKM (0.30) | PKMSMN1; SMN2 | |
| SCHEMBL2323498 | 0.86 | PKM (0.30) | PKMSMN1; SMN2 | |
| SCHEMBL2326420 | 0.86 | PKM (0.30) | PKMSMN1; SMN2 | |
| SCHEMBL3263904 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3111086 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL499832 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL1864715 | 0.72 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160300-A1 | Renin Inhibitors and Methods of Use Thereof | VITAE PHARMACEUTICALS, INC. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160300-A1 | Renin Inhibitors and Methods of Use Thereof | REN, ACE, AGTR1 | ALDH1A1 2320/4885PKM 2984/4885SMN1; SMN2 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.