Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.57 |
| ▸ | GART | P22102 | 5/20 | 0.57 |
| ▸ | TYMS | P04818 | 4/20 | 0.57 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | TLR4 | O00206 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27560842 | 0.99 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL338037 | 0.92 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL20486467 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28344641 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28135233 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL25167471 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL16583122 | 0.91 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28697708 | 0.91 | DHFR (0.55) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL3771709 | 0.91 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL15530423 | 0.91 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12458701-B2 | Bis (hydroxy benzylidene) cyclic ketone based tetra-aza corand | DESAI ARPITA (IN) | 2025-11-04 | — | — | US | disclosed |
| US-20230226194-A1 | NOVEL BIS (HYDROXY BENZYLIDENE) CYCLIC KETONE BASED TETRA-AZA CORAND | DESAI ARPITA (IN) | 2023-07-20 | — | — | US | disclosed |
| WO-2022074673-A1 | NOVEL BIS (HYDROXY BENZYLIDENE) CYCLIC KETONE BASED TETRA-AZA CORAND | DESAI DR ARPITA S (IN) | 2022-04-14 | — | — | WO | disclosed |
| EP-2651411-B1 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-3242691-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | Immunomedics, Inc. (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2017-10-05 | — | — | US | disclosed |
| EP-3218015-A2 | METHODS AND COMPOSITIONS FOR IMPROVED LABELING OF TARGETING PEPTIDES | Immunomedics, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| CN-106344927-A | Folic acid modified drug-loaded hydroxyapatite and preparation method thereof | 大连理工大学 | 2017-01-25 | — | — | CN | disclosed |
| WO-2016111797-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. (US) | 2016-07-14 | — | — | WO | disclosed |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. | 2016-07-14 | — | — | US | disclosed |
| US-20090299033-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| WO-2009135015-A2 | IMPROVED METHODS AND COMPOSITIONS FOR F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-7563433-B2 | Use in positron emission tomography for example or tissue targeted therapy; forming a F18 metal complex, and attaching the F-18 metal complex to the molecule such as peptide or antibody; improved biological half life | IMMUNOMEDICS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| WO-2009079024-A1 | IMPROVED METHODS AND COMPOSITIONS FOR F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS, INC. (US) | 2009-06-25 | — | — | WO | disclosed |
| US-20090155166-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20080253964-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| CN-101240024-A | Single-chain antibody scFv of hBAFF and application thereof in producing BAFF human source monoclonal antibody | UNIV NANJING NORMAL (CN) | 2008-08-13 | — | — | CN | disclosed |
| EP-1940386-A2 | WORTMANNIN CONJUGATES AND USES THEREOF | Beth Israel Deaconess Medical Center (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007086943-A2 | WORTMANNIN CONJUGATES AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458701-B2 | Bis (hydroxy benzylidene) cyclic ketone based tetra-aza corand | HDAC6, TBCA, TBC1D15 | DHFR 24/4885GART 4164/4885TYMS 412/4885 |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | BRS3, BRCA1, MRE11 | DHFR 3949/4885GART 3960/4885TYMS 4321/4885 |
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, TFRC, F13A1 | DHFR 2587/4885GART 941/4885TYMS 4267/4885 |
| US-20230226194-A1 | NOVEL BIS (HYDROXY BENZYLIDENE) CYCLIC KETONE BASED TETRA-AZA CORAND | HDAC6, TBCA, TBC1D15 | DHFR 35/4885GART 4140/4885TYMS 394/4885 |
| US-20090155166-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | S100A8, TFRC, F13A1 | DHFR 2661/4885GART 739/4885TYMS 3887/4885 |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | DHFR 1018/4885GART 492/4885TYMS 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.