Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938761 | 0.94 | CYP3A4 (0.61) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL3404530 | 0.92 | AKR1B1 (0.64) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL31287228 | 0.89 | EPHX2 (0.63) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL5090723 | 0.87 | AKR1B1 (0.59) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL3989919 | 0.86 | NOX4 (0.59) | POLHMEN1KMT2AKDM4EPOLB | |
| Quercetin SCHEMBL8442487 | 0.85 | MEN1 (0.70) | POLHMEN1KMT2AKDM4EPOLB | |
| Curcumin SCHEMBL20291461 | 0.84 | MEN1 (0.68) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL13846231 | 0.83 | POLH (0.59) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL15227652 | 0.81 | POLH (0.58) | POLHMEN1KMT2AKDM4EPOLB | |
| Curcumin SCHEMBL21049944 | 0.80 | MEN1 (0.62) | POLHMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891452-A | Cosmetic or dermatological composition containing at least one active principle precursor and a crosslinked poly(2-acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90% | L'OREAL (FR) | 1999-04-06 | — | — | US | claimed |
| US-5891452-A | Cosmetic or dermatological composition containing at least one active principle precursor and a crosslinked poly(2-acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90% | L'OREAL (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5607921-A | Stabilized cosmetic or dermatological composition containing several precursors of the same active agent in order to maximize its release, and use thereof | L'OREAL (FR) | 1997-03-04 | — | — | US | disclosed |