Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458892 | 0.82 | THRB (0.48) | HPGDEPHX1GPR119RECQLKDM4E | |
| SCHEMBL2391972 | 0.80 | HPGDS (0.44) | HPGDEPHX1GPR119KDM4EMAPT | |
| SCHEMBL2391975 | 0.80 | HPGDS (0.44) | HPGDEPHX1GPR119KDM4EMAPT | |
| SCHEMBL20292145 | 0.80 | HPGD (0.41) | HPGDHCAR1EPHX1GPR119CTSD | |
| SCHEMBL13216243 | 0.76 | NR1H2 (0.41) | HPGDEPHX1GPR119KDM4EMAPT | |
| SCHEMBL20292149 | 0.75 | HCAR1 (0.42) | HPGDHCAR1EPHX1GPR119CTSD | |
| SCHEMBL21608184 | 0.75 | GPR119 (0.50) | HPGDHCAR1GPR119 | |
| SCHEMBL22541491 | 0.75 | GPR119 (0.46) | HPGDEPHX1GPR119CTSDCTSE | |
| SCHEMBL23064601 | 0.74 | GPR119 (0.55) | HCAR1GPR119KDM4EPTPN2PTPN1 | |
| SCHEMBL2475425 | 0.73 | HPGD (0.52) | HPGDHCAR1EPHX1GPR119RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |
| EP-3406609-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC RECEPTOR AGONISTS | Heptares Therapeutics Limited (GB) | 2018-11-28 | — | — | EP | disclosed |
| EP-3102568-B1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS. | HEPTARES THERAPEUTICS LTD (GB) | 2018-06-27 | — | — | EP | disclosed |