Isoquercetin

Isoquercetin

SCHEMBL20292455

O=c1c(O[C@H]2O[C@@H](CO)[C@@H](O)[C@@H](O)[C@@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P4HB P07237 6/20 1.00
▸ KDM4E B2RXH2 5/20 1.00
▸ AKR1B1 P15121 5/20 1.00
▸ EPHX2 P34913 5/20 1.00
▸ GAA P10253 4/20 1.00
▸ POLB P06746 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ CA12 O43570 3/20 1.00
▸ CA2 P00918 3/20 1.00
▸ CA4 P22748 3/20 1.00
▸ CA7 P43166 3/20 1.00
▸ ALPL P05186 2/20 1.00
▸ ALPI P09923 2/20 1.00
▸ SLCO2B1 O94956 2/20 1.00
▸ MAOA P21397 2/20 1.00
▸ XDH P47989 2/20 1.00
▸ ADRA2C P18825 1/20 1.00
▸ NOX4 Q9NPH5 1/20 1.00
▸ KDM1A O60341 1/20 1.00
▸ HMGB1 P09429 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoquercetin SCHEMBL23249 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Miquelianin SCHEMBL1643868 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19490596 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19212904 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL20150699 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL9916971 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL5312085 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL12566342 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL21244358 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL22495101 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2812005-B1 POLYHYDROXYLATED PENTACYCLIC TRITERPENE ACIDS AS HMG-COA REDUCTASE INHIBITORS PRAIRIE BERRY EUROPE GMBH (DE) 2018-06-27 — — EP claimed
CN-102397285-A Application of hyperin in preparing medicine for treating vascular dementia UNIV XINXIANG MEDICAL 2012-04-04 — — CN claimed
CN-101167805-B Use of medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction in preparing medicine for hepatitis B virus UNIV FUDAN 2010-12-29 — — CN claimed
CN-101167805-A Medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction and use thereof UNIV FUDAN (CN) 2008-04-30 — — CN claimed
EP-2812005-B1 POLYHYDROXYLATED PENTACYCLIC TRITERPENE ACIDS AS HMG-COA REDUCTASE INHIBITORS PRAIRIE BERRY EUROPE GMBH (DE) 2018-06-27 — — EP disclosed
CN-102210747-A Hypoglycemic pharmaceutical preparation and preparation method thereof UNIV TSINGHUA RES INST 2011-10-12 — — CN disclosed
CN-101167805-B Use of medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction in preparing medicine for hepatitis B virus UNIV FUDAN 2010-12-29 — — CN disclosed
CN-101167805-B Use of medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction in preparing medicine for hepatitis B virus UNIV FUDAN 2010-12-29 — — CN disclosed
CN-101167805-A Medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction and use thereof UNIV FUDAN (CN) 2008-04-30 — — CN disclosed
CN-101167805-A Medicinal composition containing lotus leaves and hypericum japonicum total flavone extraction and use thereof UNIV FUDAN (CN) 2008-04-30 — — CN disclosed
CN-1990479-A 3-alkoxy substituted-2, 5, 7-tri-substituted benzopyran-4-ketones compounds, preparing method thereof and pharmaceutical compounds containing same SHANGHAI INST MATERIA MEDICA (CN) 2007-07-04 — — CN disclosed
CN-1191262-C Cranesbill total flavonoid extract and use in preparation of anti-virus medicine FUHAN UNIV (CN) 2005-03-02 — — CN disclosed
CN-1434052-A Cranesbill total flavonoid extract and use in preparation of anti-virus medicine FUHAN UNIV (CN) 2003-08-06 — — CN disclosed
CN-1434052-A Cranesbill total flavonoid extract and use in preparation of anti-virus medicine FUHAN UNIV (CN) 2003-08-06 — — CN disclosed
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