Miquelianin

Miquelianin

SCHEMBL1643868

O=c1c(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P4HB P07237 6/20 1.00
▸ KDM4E B2RXH2 5/20 1.00
▸ AKR1B1 P15121 5/20 1.00
▸ EPHX2 P34913 5/20 1.00
▸ GAA P10253 4/20 1.00
▸ POLB P06746 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ CA12 O43570 3/20 1.00
▸ CA2 P00918 3/20 1.00
▸ CA4 P22748 3/20 1.00
▸ CA7 P43166 3/20 1.00
▸ ALPL P05186 2/20 1.00
▸ ALPI P09923 2/20 1.00
▸ SLCO2B1 O94956 2/20 1.00
▸ MAOA P21397 2/20 1.00
▸ XDH P47989 2/20 1.00
▸ ADRA2C P18825 1/20 1.00
▸ NOX4 Q9NPH5 1/20 1.00
▸ KDM1A O60341 1/20 1.00
▸ HMGB1 P09429 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoquercetin SCHEMBL23249 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19490596 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL19212904 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL20150699 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL9916971 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL5312085 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL12566342 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL21244358 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL22495101 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA
Isoquercetin SCHEMBL20292455 1.00 P4HB (1.00) P4HBKDM4EAKR1B1EPHX2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994923-A2 Cosmetic and dermatological compositions for dry skin Henkel AG & Co. KGaA (DE) 2008-11-26 — — EP claimed
EP-1790330-A2 Cosmetic and dermatological compositions containing oligopeptides and apple extract Henkel Kommanditgesellschaft auf Aktien (DE) 2007-05-30 — — EP claimed
EP-1634576-A1 DNA repair enzymes and oligopeptides containing cosmetic and dermatological compositions Henkel Kommanditgesellschaft auf Aktien (DE) 2006-03-15 — — EP claimed
US-20040234466-A1 Beta-glucuronidase inhibitors for use in deodorants and antiperspirants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-11-25 — — US claimed
EP-1441691-A2 BETA-GLUCURONIDASE INHIBITORS FOR USE IN DEODORANTS AND ANTIPERSPIRANTS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-08-04 — — EP claimed
EP-1430879-A2 Arylsulfatase inhibitors in deodorants and antiperspirants Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-23 — — EP claimed
EP-1430933-A2 Cosmetic and pharmaceutical compositions comprising steroid sulfatase inhibitors and their use for the reduction of hair loss Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-23 — — EP claimed
EP-1428520-A2 Lipase inhibitors in deodorants and antiperspirants Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-16 — — EP claimed
EP-1393518-A2 ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-03-03 — — EP claimed
WO-2003039505-A2 ss-GLUCURONIDASE INHIBITORS FOR USE IN DEODORANTS AND ANTIPERSPIRANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-05-15 — — WO claimed
WO-2001099376-A2 ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 — — WO claimed
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 — — US disclosed
US-10981084-B2 Use of coconut water as extraction solvent BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2021-04-20 — — US disclosed
CN-105838758-B Water-soluble phenolic derivatives for cosmetic and therapeutic applications on the skin 利布莱根公司 2020-03-06 — — CN disclosed
US-20190336884-A1 USE OF COCONUT WATER AS EXTRACTION SOLVENT BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2019-11-07 — — US disclosed
EP-1430882-A2 Combinations of antioxidants containing 6,7-disubstituted 2,2-dialkylchromanes or -chromenes Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-23 — — EP disclosed
EP-1430879-A2 Arylsulfatase inhibitors in deodorants and antiperspirants Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-23 — — EP disclosed
EP-1428520-A2 Lipase inhibitors in deodorants and antiperspirants Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-16 — — EP disclosed
EP-1393518-A2 ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-03-03 — — EP disclosed
WO-2001099376-A2 ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234918-B2 Methods for botanical and/or algae extraction ALG1, ALG8, CUTA P4HB 3427/4885KDM4E 4367/4885AKR1B1 2466/4885
US-20040234466-A1 Beta-glucuronidase inhibitors for use in deodorants and antiperspirants GUSB, PON1, IDUA P4HB 537/4885KDM4E 3145/4885AKR1B1 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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