Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 5/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | CA12 | O43570 | 3/20 | 1.00 |
| ▸ | CA2 | P00918 | 3/20 | 1.00 |
| ▸ | CA4 | P22748 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 3/20 | 1.00 |
| ▸ | ALPL | P05186 | 2/20 | 1.00 |
| ▸ | ALPI | P09923 | 2/20 | 1.00 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | XDH | P47989 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 1.00 |
| ▸ | KDM1A | O60341 | 1/20 | 1.00 |
| ▸ | HMGB1 | P09429 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoquercetin SCHEMBL23249 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Miquelianin SCHEMBL1643868 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL19490596 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL19212904 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL20150699 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL9916971 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL5312085 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL21244358 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL22495101 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA | |
| Isoquercetin SCHEMBL20292455 | 1.00 | P4HB (1.00) | P4HBKDM4EAKR1B1EPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872241-B2 | Compositions and methods for reducing major thrombotic events in cancer patients | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230310477-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ABELIOPHYLLUM DISTICHUM EXTRACT AS ACTIVE INGREDIENT FOR TREATING ANDROGEN RECEPTOR-RELATED DISEASE | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (KR) | 2023-10-05 | — | — | US | disclosed |
| US-11744827-B2 | Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-09-05 | — | — | US | disclosed |
| US-20200330447-A1 | CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW COMBINATIONS OF SUCH DRUGS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2020-10-22 | — | — | US | disclosed |
| US-10695338-B2 | Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2020-06-30 | — | — | US | disclosed |
| US-20200171064-A1 | COMPOSITIONS AND METHODS FOR REDUCING MAJOR THROMBOTIC EVENTS IN CANCER PATIENTS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2020-06-04 | — | — | US | disclosed |
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITAET HAMBURG (DE) | 2019-04-04 | — | — | US | disclosed |
| US-20180133208-A1 | CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW COMBINATIONS OF SUCH DRUGS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2018-05-17 | — | — | US | disclosed |
| US-20110136245-A1 | SYNERGISTIC INTERACTIONS OF PHENOLIC COMPOUNDS FOUND IN FOOD | BRIGHAM YOUNG UNIVERSITY | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200171064-A1 | COMPOSITIONS AND METHODS FOR REDUCING MAJOR THROMBOTIC EVENTS IN CANCER PATIENTS | SELP, SELE, SELPLG | P4HB 424/4885KDM4E 3842/4885AKR1B1 1862/4885 |
| US-20230310477-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ABELIOPHYLLUM DISTICHUM EXTRACT AS ACTIVE INGREDIENT FOR TREATING ANDROGEN RECEPTOR-RELATED DISEASE | AR, BPHL, APLNR | P4HB 4730/4885KDM4E 2367/4885AKR1B1 322/4885 |
| US-11872241-B2 | Compositions and methods for reducing major thrombotic events in cancer patients | SELP, SELE, SELPLG | P4HB 424/4885KDM4E 3842/4885AKR1B1 1862/4885 |
| US-11744827-B2 | Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs | SLC6A1, CTSA, CTSS | P4HB 4693/4885KDM4E 1463/4885AKR1B1 3182/4885 |
| US-20180133208-A1 | CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW COMBINATIONS OF SUCH DRUGS | SLC6A1, CTSA, CTSS | P4HB 4693/4885KDM4E 1463/4885AKR1B1 3182/4885 |
| US-20200330447-A1 | CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW COMBINATIONS OF SUCH DRUGS | SLC6A1, CTSA, CTSS | P4HB 4693/4885KDM4E 1463/4885AKR1B1 3182/4885 |
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | LRAT, TYR, CUTA | P4HB 4463/4885KDM4E 1188/4885AKR1B1 374/4885 |
| US-10695338-B2 | Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs | SLC6A1, CTSA, CTSS | P4HB 4693/4885KDM4E 1463/4885AKR1B1 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.