SCHEMBL2029313

SCHEMBL2029313

Cc1cn([C@H]2CC(OCC(=O)CCC(=O)O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.65
TK1 P04183 5/20 0.56
LMNA P02545 2/20 0.54
TSHR P16473 2/20 0.54
ALB P02768 1/20 0.54
PKM P14618 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
CYP2D6 P10635 1/20 0.54
TK2 O00142 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2029315 1.00 RNASE1 (0.65) RNASE1TK1LMNATSHRALB
SCHEMBL3230615 0.91 RNASE1 (0.70) RNASE1TK1LMNATSHRALB
SCHEMBL3230623 0.91 RNASE1 (0.70) RNASE1TK1LMNATSHRALB
SCHEMBL19407973 0.87 RNASE1 (0.71) RNASE1TK1LMNATSHRALB
SCHEMBL3337696 0.87 RNASE1 (0.71) RNASE1TK1LMNATSHRALB
SCHEMBL2056647 0.84 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
Doxribtimine SCHEMBL2985309 0.83 TK1 (0.65) RNASE1TK1LMNATK2
SCHEMBL6248265 0.83 RNASE1 (0.68) RNASE1TK1LMNATSHRALB
SCHEMBL16360133 0.83 RNASE1 (0.68) RNASE1TK1LMNATSHRALB
SCHEMBL26571124 0.83 RNASE1 (0.68) RNASE1TK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8552175-B2 Sulfur transfer reagents for oligonucleotide synthesis A.M. Chemicals, Inc. (US) 2013-10-08 US disclosed
US-20110137021-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS A.M. Chemicals, Inc. 2011-06-09 US disclosed
US-7723528-B2 Sulfur transfer reagents for oligonucleotide synthesis AM CHEMICALS LLC (US) 2010-05-25 US disclosed
US-20090306358-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC 2009-12-10 US disclosed
WO-2009148719-A1 SULFER TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC (US) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306358-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS POLRMT, TST, DNTT RNASE1 2429/4885TK1 39/4885LMNA 1917/4885
US-20110137021-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS TST, POLRMT, DNTT RNASE1 2272/4885TK1 32/4885LMNA 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.