SCHEMBL20300

SCHEMBL20300

CC(C)(c1ccc(O)cc1)c1ccc(O[PH](=O)Oc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
CYP3A4 P08684 2/20 0.59
AR P10275 1/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
LTA4H P09960 1/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 8/20 0.40
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910592 0.92 SMN1; SMN2 (0.45) ALDH1A1ESR1ESR2CYP3A4NPC1
SCHEMBL10295109 0.86 LTA4H (0.58) ESR1ESR2SLC6A2SLC6A3LTA4H
SCHEMBL9910584 0.85 CA4 (0.47) ALDH1A1ESR1ESR2CYP3A4HSD17B10
SCHEMBL19159265 0.84 ALDH1A1 (0.56) ALDH1A1ESR1ESR2CYP3A4AR
SCHEMBL10295094 0.81 ESR1 (0.57) ALDH1A1ESR1ESR2CYP3A4AR
SCHEMBL677719 0.81 CYP3A4 (0.41) ALDH1A1ESR1ESR2CYP3A4TSHR
SCHEMBL12646235 0.81 MMP3 (0.52) ESR1ESR2SLC6A2SLC6A3LTA4H
SCHEMBL12994049 0.81 ESR1 (0.70) ALDH1A1ESR1ESR2CYP3A4AR
Phenol SCHEMBL27580067 0.80 CA12 (0.50) ESR1ESR2CYP3A4HPGDTSHR
SCHEMBL19280460 0.80 SMN1; SMN2 (0.45) ALDH1A1ESR1ESR2CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170298222-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED ARTICLE THEREOF LG CHEM, LTD. (KR) 2017-10-19 US disclosed
US-20170204263-A1 FLAME RETARDANT RESIN COMPOSITION AND CONNECTION STRUCTURE FOR SOLAR POWER GENERATION MODULE ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-07-20 US disclosed
US-9637632-B2 Method for the production and stabilization of impact-modified polycarbonate compositions using diluted solutions of acidic compounds COVESTRO DEUTSCHLAND AG (DE) 2017-05-02 US disclosed
US-9617417-B2 Impact-modified polycarbonate compositions having a good combination of natural color, hydrolytic stability and melt stability COVESTRO DEUTSCHLAND AG (DE) 2017-04-11 US disclosed
US-20170002247-A1 THERMALLY CONDUCTIVE THERMOPLASTIC COMPOSITIONS FEATURING BALANCED PROCESSABILITY COVESTRO DEUTSCHLAND AG (DE) 2017-01-05 US disclosed
EP-2382269-B1 FLAME-PROTECTED IMPACT STRENGTH MODIFIED POLYCARBONATE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2016-12-14 EP disclosed
US-20160280910-A1 GLASS-FIBRE REINFORCED POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2016-09-29 US disclosed
US-20160257794-A1 FIBER COMPOSITE MATERIAL, USE THEREFOR, AND METHOD FOR THE PRODUCTION THEREOF COVESTRO DEUTSCHLAND AG (DE) 2016-09-08 US disclosed
US-20160244609-A1 Polycarbonate compositions having improved adhesion to polyurethane layers COVESTRO DEUTSCHLAND AG (DE) 2016-08-25 US disclosed
US-20160244608-A1 Polycarbonate Compositions Having Improved Adhesion to Polyurethane Layers COVESTRO DEUTSCHLAND AG (DE) 2016-08-25 US disclosed
US-7358290-B2 Polycarbonate molding compositions with improved hydrolysis resistance BAYER MATERIALSCIENCE AG (DE) 2008-04-15 US disclosed
US-7319116-B2 Flame-resistant polycarbonate molding composition modified with a graft polymer BAYER MATERIALSCIENCE AG (DE) 2008-01-15 US disclosed
US-20070225441-A1 Flame resistant, impact modified polycarbonate compositions BAYER MATERIALSCIENCE AG 2007-09-27 US disclosed
US-20070225413-A1 Flameproofed impact-strength-modified poly(ester)carbonate compositions COVESTRO DEUTSCHLAND AG (DE) 2007-09-27 US disclosed
US-20070225412-A1 Flameproofed impact-strength-modified poly(ester)carbonate compositions COVESTRO DEUTSCHLAND AG (DE) 2007-09-27 US disclosed
EP-1399512-B1 MODIFIED IMPACT-RESISTANT POLYMER COMPOSITION BAYER MATERIALSCIENCE AG (DE) 2007-08-15 EP disclosed
WO-2007065577-A1 POLYCARBONATE MOLDING COMPOUNDS BAYER MATERIALSCIENCE AG (DE) 2007-06-14 WO disclosed
US-20070135568-A1 comprises polycarbonate resin, a first graft polymer, a first free copolymer, a second graft polymer and a second free copolymer; improved balance of melt flowability and ductility, good resistance to hydrolysis and process stability BAYER MATERIALSCIENCE AG 2007-06-14 US disclosed
US-7223812-B2 Impact-modified polymer composition BAYER AKTIENGESELLSCHAFT (DE) 2007-05-29 US disclosed
US-20070060678-A1 Thermoplastic molding composition and articles thermoformed therefrom COVESTRO DEUTSCHLAND AG (DE) 2007-03-15 US disclosed