Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NOS2 | P35228 | 5/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | BHMT | Q93088 | 9/20 | 0.44 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469425 | 0.87 | NOS2 (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL19469422 | 0.87 | NOS2 (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL19469426 | 0.87 | BHMT (0.51) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL28303734 | 0.86 | KDM4E (0.62) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Cystine SCHEMBL28150844 | 0.84 | MAPT (0.68) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL28342967 | 0.82 | ALOX15 (0.70) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL9016357 | 0.82 | ALOX15 (0.70) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL10351403 | 0.81 | MAPT (0.64) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Cystine SCHEMBL7049689 | 0.81 | MAPT (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL1069666 | 0.80 | KDM4E (0.78) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554492-A1 | AMINO ACID COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISEASES | Axcella Health Inc. (US) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018118941-A1 | AMINO ACID COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISEASES | AXCELLA HEALTH INC. (US) | 2018-06-28 | — | — | WO | disclosed |