SCHEMBL2030480

SCHEMBL2030480

CC1(C)CC(C(=O)NCCN=C=S)C(C)(C)N1[O]

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 6/20 0.39
NFE2L2 Q16236 6/20 0.39
SLC2A1 P11166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8670419 0.92 KEAP1 (0.46) KEAP1NFE2L2
SCHEMBL8411554 0.88 KEAP1 (0.35) KEAP1NFE2L2
SCHEMBL2024876 0.88 KEAP1 (0.40) KEAP1NFE2L2SLC2A1
SCHEMBL28625375 0.85 KEAP1 (0.38) KEAP1NFE2L2SLC2A1
SCHEMBL8676534 0.83 GAA (0.31)
SCHEMBL11803872 0.75 FPR3 (0.35)
SCHEMBL9439471 0.75 CYP3A4 (0.33)
SCHEMBL28625373 0.73 KEAP1 (0.39) KEAP1NFE2L2
SCHEMBL2024934 0.72 CYP3A4 (0.30)
SCHEMBL8673309 0.70 OPRM1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3065944-B1 MODIFICATION OF POLYAMIDES ARKEMA INC (US) 2022-01-19 EP claimed
US-5714510-A Topical proxyl composition and method PROCTOR PETER H (US) 1998-02-03 US claimed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP claimed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed
US-20240117156-A1 ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES ARKEMA INC (US) 2024-04-11 US disclosed
US-11873381-B2 Accelerated peroxide-cured resin compositions having extended open times ARKEMA INC. (US) 2024-01-16 US disclosed
EP-3065944-B1 MODIFICATION OF POLYAMIDES ARKEMA INC (US) 2022-01-19 EP disclosed
US-20210009790-A1 ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES ARKEMA INC. 2021-01-14 US disclosed
EP-3755675-A1 ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES Arkema, Inc. (US) 2020-12-30 EP disclosed
WO-2019160802-A1 ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES ARKEMA INC. (US) 2019-08-22 WO disclosed
US-9663632-B2 Modification of polyamides ARKEMA INC. (US) 2017-05-30 US disclosed
US-9580527-B2 Dual cure composite resins containing uretdione and unsaturated sites COVESTRO LLC (US) 2017-02-28 US disclosed
WO-2014150712-A1 DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES BAYER MATERIAL SCIENCE LLC (US) 2014-09-25 WO disclosed
US-20140275345-A1 DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES COVESTRO LLC 2014-09-18 US disclosed
US-20120241158-A1 RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS ARKEMA INC. (US) 2012-09-27 US disclosed
WO-2011071797-A1 RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS ARKEMA INC. (US) 2011-06-16 WO disclosed
US-5714510-A Topical proxyl composition and method PROCTOR PETER H (US) 1998-02-03 US disclosed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP disclosed
EP-0327263-A1 Hair growth stimulation with nitroxide and other radicals PROCTOR, Peter H. (US) 1989-08-09 EP disclosed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO disclosed