Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030480 | 0.88 | KEAP1 (0.39) | KEAP1NFE2L2SLC2A1 | |
| SCHEMBL28625375 | 0.86 | KEAP1 (0.38) | KEAP1NFE2L2SLC2A1 | |
| SCHEMBL8670419 | 0.81 | KEAP1 (0.46) | KEAP1NFE2L2 | |
| SCHEMBL23784774 | 0.78 | GAA (0.40) | GAAL3MBTL1 | |
| SCHEMBL22315409 | 0.78 | L3MBTL1 (0.40) | GAAL3MBTL1 | |
| SCHEMBL21103465 | 0.78 | GAA (0.40) | GAAL3MBTL1 | |
| SCHEMBL8411554 | 0.77 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL18545712 | 0.77 | GAA (0.39) | GAAL3MBTL1 | |
| SCHEMBL12846024 | 0.76 | GAA (0.41) | GAAL3MBTL1 | |
| SCHEMBL18545640 | 0.76 | FPR3 (0.40) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-05 | — | — | US | disclosed |
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFONIA (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-09 | — | — | US | disclosed |
| US-9580527-B2 | Dual cure composite resins containing uretdione and unsaturated sites | COVESTRO LLC (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160200857-A1 | DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND UNSATURATED SITES | COVESTRO LLC | 2016-07-14 | — | — | US | disclosed |
| US-9175117-B2 | Dual cure composite resins containing uretdione and unsaturated sites | COVESTRO LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9102866-B2 | Radical trap in oil and gas stimulation operations | ARKEMA INC. (US) | 2015-08-11 | — | — | US | disclosed |
| WO-2014150712-A1 | DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES | BAYER MATERIAL SCIENCE LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140275345-A1 | DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES | COVESTRO LLC | 2014-09-18 | — | — | US | disclosed |
| US-20120241158-A1 | RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS | ARKEMA INC. (US) | 2012-09-27 | — | — | US | disclosed |
| WO-2011071797-A1 | RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS | ARKEMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-0661309-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | KEAP1 338/4885NFE2L2 434/4885GAA 1175/4885 |
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | KEAP1 338/4885NFE2L2 434/4885GAA 1175/4885 |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | KEAP1 348/4885NFE2L2 443/4885GAA 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.