Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.78 |
| ▸ | CCR3 | P51677 | 2/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374609 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CCR3HRH3KCNH2 | |
| SCHEMBL8091672 | 0.87 | SIGMAR1 (0.97) | SIGMAR1CCR3HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL7407431 | 0.87 | SIGMAR1 (0.97) | SIGMAR1CCR3HRH3KCNH2 | |
| SCHEMBL7409408 | 0.84 | SIGMAR1 (0.91) | SIGMAR1CCR3HRH3KCNH2ABCB1 | |
| SCHEMBL7372248 | 0.83 | CCR3 (0.84) | SIGMAR1CCR3HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL7404260 | 0.82 | SIGMAR1 (0.88) | SIGMAR1CCR3HRH3KCNH2ABCB1 | |
| SCHEMBL17023759 | 0.82 | KCNH2 (0.71) | SIGMAR1CCR3KCNH2ABCB1 | |
| SCHEMBL18590360 | 0.82 | KCNH2 (0.71) | SIGMAR1CCR3KCNH2ABCB1 | |
| SCHEMBL9388197 | 0.82 | CARM1 (0.63) | CCR3KCNH2 | |
| SCHEMBL18609512 | 0.81 | SLC6A2 (0.57) | SIGMAR1CCR3KCNH2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004701-B2 | Methods and compositions for treating infection | UNIVERSITY OF ROCHESTER (US) | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004701-B2 | Methods and compositions for treating infection | MMP8, IFNG, MPO | SIGMAR1 4344/4885CCR3 62/4885HRH3 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.