Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436779 | 0.82 | LMNA (0.40) | NOS1CYP4F2CYP4A11ALDH1A1USP2 | |
| SCHEMBL24884485 | 0.81 | KMT2A (0.34) | CYP4F2CYP4A11ALDH1A1MAPTKDM4E | |
| SCHEMBL16427552 | 0.79 | MAPT (0.33) | CYP4F2CYP4A11ALDH1A1MAPTKDM4E | |
| SCHEMBL24884285 | 0.79 | CDK8 (0.37) | CYP4F2CYP4A11ALDH1A1MAPTKDM4E | |
| SCHEMBL30527326 | 0.79 | MAPT (0.33) | CYP4F2CYP4A11MAPTKDM4EKMT2A | |
| SCHEMBL21241776 | 0.78 | GAA (0.40) | NOS1CYP4F2CYP4A11ALDH1A1USP2 | |
| SCHEMBL21241772 | 0.78 | CYP4F2 (0.43) | NOS1CYP4F2CYP4A11ALDH1A1USP2 | |
| SCHEMBL22305675 | 0.78 | CYP4F2 (0.35) | NOS1CYP4F2CYP4A11ALDH1A1USP2 | |
| SCHEMBL20306392 | 0.77 | CYP4F2 (0.43) | NOS1CYP4F2CYP4A11ALDH1A1USP2 | |
| SCHEMBL24737152 | 0.75 | NOS1 (0.41) | NOS1CYP4F2CYP4A11ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005774-B2 | Syk inhibitors | GILEAD SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005774-B2 | Syk inhibitors | SYK, BTK, LYN | NOS1 902/4885CYP4F2 3958/4885CYP4A11 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.