Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24884220 | 0.78 | NOS1 (0.35) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL24813878 | 0.77 | MAPT (0.36) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL12436779 | 0.77 | LMNA (0.40) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL20306386 | 0.75 | NOS1 (0.44) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL6904862 | 0.74 | MAPT (0.38) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL21166137 | 0.74 | MAPT (0.34) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL21241772 | 0.72 | CYP4F2 (0.43) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL22305675 | 0.72 | CYP4F2 (0.35) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL21241776 | 0.72 | GAA (0.40) | NOS1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL21581037 | 0.72 | ALDH1A1 (0.33) | NOS1MAPTRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289847-A1 | PIM KINASE INHIBITOR | Hangzhou Biosun Pharmaceutical Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022166860-A1 | PIM KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2022-08-11 | — | — | WO | disclosed |