Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996413 | 0.80 | KDR (0.35) | STING1AAK1 | |
| Hydrochloric Acid SCHEMBL1071131 | 0.80 | KDR (0.35) | STING1AAK1 | |
| Hydrochloric Acid SCHEMBL3494749 | 0.73 | STING1 (0.36) | STING1AAK1 | |
| Hydrochloric Acid SCHEMBL2897201 | 0.73 | STING1 (0.36) | STING1AAK1 | |
| SCHEMBL12934499 | 0.73 | P2RX3 (0.39) | — | |
| SCHEMBL3496077 | 0.71 | STING1 (0.35) | STING1AAK1 | |
| Hydrochloric Acid SCHEMBL1071132 | 0.71 | HTR3E (0.37) | STING1 | |
| SCHEMBL12963793 | 0.70 | STING1 (0.30) | STING1 | |
| SCHEMBL1071024 | 0.68 | PDE4B (0.33) | STING1 | |
| SCHEMBL8224387 | 0.67 | KDR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268285-B1 | THERAPEUTIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | disclosed |