Acetic Acid

Acetic Acid

SCHEMBL2031476

C=CCn1cc[n+](C)c1.CC(=O)[O-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
PLA2G1B P04054 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL14739087 0.93 FDPS (0.37) FDPSSMN1; SMN2LMNAMEN1APAF1
Propionic Acid SCHEMBL28053580 0.90 FDPS (0.39) FDPSSMN1; SMN2LMNAMEN1APAF1
Glycine SCHEMBL31241250 0.89 FDPS (0.38) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL205339 0.88
Urea SCHEMBL29001562 0.87 SMN1; SMN2 (0.39) FDPSSMN1; SMN2LMNAMEN1APAF1
Butyric Acid SCHEMBL28053654 0.86 FFAR3 (0.40) FDPSSMN1; SMN2LMNAMEN1APAF1
Formic Acid SCHEMBL17076871 0.86 FDPS (0.40) FDPSSMN1; SMN2LMNAMEN1APAF1
Iodide SCHEMBL898865 0.86 MEN1 (0.43) FDPSSMN1; SMN2LMNAMEN1APAF1
Fluoride Ion SCHEMBL4200937 0.86 SMN1; SMN2 (0.43) FDPSSMN1; SMN2LMNAMEN1APAF1
Bromide SCHEMBL21777067 0.86 SMN1; SMN2 (0.43) FDPSSMN1; SMN2LMNAMEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
CN-115260839-B Use of ionic polysaccharide derivatives as antifog coating materials 中国科学院化学研究所 2023-04-14 CN claimed
CN-115634315-A Regenerated cellulose-based blood vessel or blood vessel patch and preparation method thereof 华南理工大学 2023-01-24 CN claimed
CN-115215943-A Organic room temperature phosphorescent polymer material and preparation method and application thereof 中国科学院化学研究所 2022-10-21 CN claimed
CN-111621648-B Silver solution and preparation method thereof 中国科学院化学研究所 2021-08-31 CN claimed
CN-109111516-B Method for extracting wool keratin 浙江理工大学 2021-08-27 CN claimed
CN-112816530-A Preparation method of photoelectrochemical immunosensor for detecting keratin 浙江理工大学 2021-05-18 CN claimed
CN-110130094-B Activated plant fiber, preparation method thereof and application thereof in polylactic acid composite material 东华大学 2020-12-22 CN claimed
CN-112064392-A Biomass pretreatment composition and biomass pretreatment method 中国科学院化学研究所 2020-12-11 CN claimed
CN-111840569-A PH-responsive drug-loaded nanoparticle 嘉兴市轩禾园艺技术有限公司 2020-10-30 CN claimed
CN-111618311-A Silver nanoparticle dispersion liquid and preparation method and application thereof 中国科学院化学研究所 2020-09-04 CN claimed
CN-111003842-A Environment-friendly treatment method of papermaking deinking wastewater 李洪 2020-04-14 CN claimed
US-9862982-B2 Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-09 US claimed
US-20170029856-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-02 US claimed
US-20140007497-A1 BIOREFINING COMPOUNDS AND ORGANOCATALYTIC UPGRADING METHODS UNITED STATES DEPARTMENT OF ENERGY 2014-01-09 US claimed
US-8420732-B2 Polybenzimidazole solution in an ionic liquid PBI PERFORMANCE PRODUCTS, INC. (US) 2013-04-16 US claimed
US-20130023015-A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-24 US claimed
WO-2012087442-A1 POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID PBI PERFORMANCE PRODUCTS, INC. (US) 2012-06-28 WO claimed
US-20120142830-A1 POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID DAWKINS BOBBY G (US) 2012-06-07 US claimed
US-20110152413-A1 POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID PBI PERFORMANCE PRODUCTS, INC. 2011-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140007497-A1 BIOREFINING COMPOUNDS AND ORGANOCATALYTIC UPGRADING METHODS HPD, HMOX2, DUOX2 FDPS 42/4885SMN1; SMN2 3381/4885LMNA 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.