Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685538 | 0.83 | CA2 (0.53) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL19301013 | 0.83 | CA2 (0.53) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL12199638 | 0.82 | CA2 (0.49) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL15956257 | 0.81 | CA2 (0.51) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL12199633 | 0.81 | CA2 (0.51) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL12572608 | 0.81 | CA2 (0.51) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL25819885 | 0.81 | CA2 (0.48) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL9080283 | 0.80 | CA2 (0.50) | CA2LMNAPOLB | |
| SCHEMBL21135532 | 0.80 | CA2 (0.50) | CA2LMNAPOLB | |
| SCHEMBL3188329 | 0.80 | CA2 (0.50) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | L'OREAL (FR) | 2022-10-04 | — | — | US | disclosed |
| EP-2734180-B1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | OREAL (FR) | 2021-03-31 | — | — | EP | disclosed |
| EP-2734499-B1 | MEROCYANINE DERIVATIVES | BASF SE (DE) | 2020-06-24 | — | — | EP | disclosed |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-02 | — | — | US | disclosed |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-02 | — | — | US | disclosed |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-02 | — | — | US | disclosed |
| US-9551722-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-24 | — | — | US | disclosed |
| US-9551722-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-24 | — | — | US | disclosed |
| US-9551722-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-24 | — | — | US | disclosed |
| US-9550730-B2 | Merocyanine derivatives | BASF SE (DE) | 2017-01-24 | — | — | US | disclosed |
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2013-03-14 | — | — | US | disclosed |
| WO-2013011480-A1 | MEROCYANINE DERIVATIVES | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| EP-2547314-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'Oréal (FR) | 2013-01-23 | — | — | EP | disclosed |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-29 | — | — | US | disclosed |
| EP-2509940-A2 | AMYLOID BINDING AGENTS | The Regents of the University of California (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011113719-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011072257-A2 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011072257-A2 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | DDT, PCCA, DDC | CA2 381/4885ALDH1A1 1102/4885NPSR1 4847/4885 |
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | KRT18, LAGE3, TYR | CA2 3080/4885ALDH1A1 1018/4885NPSR1 4574/4885 |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | APP, APBA1, PSEN1 | CA2 2146/4885ALDH1A1 3897/4885NPSR1 2925/4885 |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | APBA1, APP, PSEN1 | CA2 2602/4885ALDH1A1 4267/4885NPSR1 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.