Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.45 |
| ▸ | SGK1 | O00141 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 7/20 | 0.44 |
| ▸ | ITK | Q08881 | 7/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410712 | 0.87 | SGK1 (0.46) | SGK1BTKITKMETCLK1 | |
| SCHEMBL31403510 | 0.84 | AXL (0.48) | AXLCAMKK2SGK1BTKITK | |
| SCHEMBL30731289 | 0.80 | AXL (0.45) | AXLCAMKK2SGK1ITKHCAR3 | |
| SCHEMBL22554109 | 0.80 | AXL (0.45) | AXLCAMKK2SGK1ITKHCAR3 | |
| SCHEMBL2671287 | 0.80 | AXL (0.45) | AXLCAMKK2SGK1BTKITK | |
| SCHEMBL20292915 | 0.80 | AXL (0.48) | AXLCAMKK2SGK1ITKHCAR3 | |
| SCHEMBL29564788 | 0.80 | AXL (0.45) | AXLCAMKK2SGK1BTKITK | |
| SCHEMBL13387062 | 0.78 | AXL (0.44) | AXLCAMKK2SGK1ITKCLK1 | |
| SCHEMBL22578328 | 0.76 | AXL (0.42) | AXLCAMKK2SGK1ITKHCAR3 | |
| SCHEMBL7921128 | 0.74 | MET (0.46) | AXLBTKITKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-4183786-A1 | DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES | Felicitex Therapeutics, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-3558321-B1 | DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES | FELICITEX THERAPEUTICS INC (US) | 2023-02-01 | — | — | EP | disclosed |
| WO-2018119039-A1 | DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES | FELICITEX THERAPEUTICS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |