Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21950092 | 0.86 | TRPA1 (0.32) | — | |
| SCHEMBL19559238 | 0.86 | TRPA1 (0.32) | — | |
| SCHEMBL21698742 | 0.86 | TRPA1 (0.32) | — | |
| SCHEMBL8368347 | 0.85 | SIGMAR1 (0.37) | SIGMAR1ADRA1B | |
| SCHEMBL24393441 | 0.81 | ACHE (0.40) | SIGMAR1ADRA1B | |
| SCHEMBL2076710 | 0.80 | — | — | |
| SCHEMBL16559114 | 0.78 | OPRM1 (0.31) | — | |
| SCHEMBL18348230 | 0.78 | — | — | |
| SCHEMBL12849318 | 0.77 | SIGMAR1 (0.32) | SIGMAR1ADRA1B | |
| SCHEMBL5687213 | 0.77 | SIGMAR1 (0.32) | SIGMAR1ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2018119448-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | Arvinas, Inc. (US) | 2018-06-28 | — | — | WO | disclosed |