SCHEMBL203249

SCHEMBL203249

O=C(OCCC1CC2C=CC1C2)c1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 3/20 0.48
SCN2A Q99250 3/20 0.48
SCN3A Q9NY46 3/20 0.48
CHRNB2 P17787 7/20 0.45
CHRNA4 P43681 7/20 0.45
CHRNB4 P30926 6/20 0.45
CHRNA3 P32297 6/20 0.45
KDM4E B2RXH2 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 1/20 0.40
PKM P14618 1/20 0.37
LMNA P02545 1/20 0.37
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201988 0.88 CHRNB2 (0.56) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL12634161 0.84 TDP1 (0.52) KDM4ETDP1ALDH1A1PKMLMNA
SCHEMBL203802 0.83 KDM4E (0.45) SCN1ASCN2ASCN3AKDM4ETDP1
SCHEMBL12634158 0.81 PTGS2 (0.48) KDM4ETDP1ALDH1A1LMNA
SCHEMBL200409 0.81 HRH3 (0.46) KDM4ETDP1ALDH1A1
SCHEMBL201541 0.80 NPC1 (0.41) KDM4ETDP1ALDH1A1
SCHEMBL20375119 0.77 TP53 (0.48) KDM4EALDH1A1LMNA
SCHEMBL29419414 0.77 TP53 (0.48) KDM4EALDH1A1LMNA
SCHEMBL18560859 0.77 TP53 (0.48) KDM4EALDH1A1LMNA
SCHEMBL200326 0.76 TDP1 (0.46) KDM4ETDP1ALDH1A1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed