Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817736 | 1.00 | PPARA (0.61) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL18630211 | 1.00 | PPARA (0.61) | PPARAFOLH1MMEPPARGSLC1A1 | |
| Hydrochloric Acid SCHEMBL22500531 | 0.98 | PPARA (0.60) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL13844843 | 0.89 | PPARA (0.53) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL20804457 | 0.89 | PPARA (0.53) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL13227780 | 0.89 | PPARA (0.53) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL1414148 | 0.89 | PPARA (0.53) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL13013213 | 0.89 | PPARA (0.53) | PPARAFOLH1MMEPPARGSLC1A1 | |
| SCHEMBL13710930 | 0.87 | PPARA (0.52) | PPARAFOLH1MMEPPARGSLC1A1 | |
| Hydrochloric Acid SCHEMBL31612159 | 0.87 | PPARA (0.52) | PPARAFOLH1MMEPPARGSLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565518-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2026-03-03 | — | — | US | disclosed |
| US-20240262867-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2024-08-08 | — | — | US | disclosed |
| US-12049521-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-30 | — | — | US | disclosed |
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| EP-4308575-A1 | MACROCYCLES AS CFTR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | disclosed |
| CN-115515937-A | Dimers for the synthesis of peptidomimetics | 范因斯坦医学研究院 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022194399-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-22 | — | — | WO | disclosed |
| EP-3287458-B1 | HYBRID CYCLIC LIBRARIES AND SCREENING THEREOF | UNIV JOHNS HOPKINS (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-2061886-B1 | Small cationic immunomodulatory peptides | UNIV BRITISH COLUMBIA (CA) | 2014-05-07 | — | — | EP | disclosed |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | THE JOHNS HOPKINS UNIVERSITY | 2014-03-13 | — | — | US | disclosed |
| US-20130266597-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-10-10 | — | — | US | disclosed |
| EP-2646440-A2 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | The Johns Hopkins University (US) | 2013-10-09 | — | — | EP | disclosed |
| US-8343475-B2 | Small cationic antimicrobial peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-01-01 | — | — | US | disclosed |
| WO-2012075048-A2 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-07 | — | — | WO | disclosed |
| US-20110236429-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-09-29 | — | — | US | disclosed |
| US-20110150917-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-06-23 | — | — | US | disclosed |
| EP-2061886-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | The University of British Columbia (CA) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008022444-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565518-B2 | Hybrid cyclic libraries and screens thereof | NOLC1, BCL6, CHP1 | PPARA 4500/4885FOLH1 3923/4885MME 3805/4885 |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | CACYBP, HSPBP1, PEBP1 | PPARA 4333/4885FOLH1 2167/4885MME 2656/4885 |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | CHI3L1, CHI3L2, CHIA | PPARA 4708/4885FOLH1 1966/4885MME 392/4885 |
| US-12049521-B2 | Hybrid cyclic libraries and screens thereof | CACYBP, HSPBP1, PEBP1 | PPARA 4333/4885FOLH1 2167/4885MME 2656/4885 |
| US-20240262867-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | PPARA 4333/4885FOLH1 2167/4885MME 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.