Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | WHR1 | P49842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20331732 | 0.92 | ABL1 (0.32) | PDE9AABL1MAP4K1TTK | |
| SCHEMBL21252104 | 0.90 | ABL1 (0.36) | PDE9AABL1MAP4K1TTKWHR1 | |
| SCHEMBL21252283 | 0.90 | MAP3K12 (0.32) | MAP4K1 | |
| SCHEMBL21240252 | 0.90 | PDE9A (0.37) | PDE9AMAP4K1TTK | |
| SCHEMBL21252119 | 0.89 | PDE9A (0.36) | PDE9ATTK | |
| SCHEMBL21240428 | 0.83 | PDE9A (0.40) | PDE9AABL1MAP4K1TTKWHR1 | |
| SCHEMBL21252007 | 0.83 | PIK3CA (0.36) | ABL1MAP4K1TTKWHR1 | |
| SCHEMBL21252282 | 0.82 | JAK2 (0.34) | TTK | |
| SCHEMBL21252476 | 0.81 | MAP3K12 (0.34) | MAP4K1 | |
| SCHEMBL21240064 | 0.81 | PDE9A (0.32) | PDE9AMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018113584-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2018-06-28 | — | — | WO | disclosed |