Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 6/20 | 0.35 |
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | TEK | Q02763 | 6/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508548 | 0.69 | LCK (0.53) | LCKKDRTEKSRCKDM4E | |
| SCHEMBL6862112 | 0.69 | LCK (0.53) | LCKKDRTEKSRCKDM4E | |
| SCHEMBL6250271 | 0.67 | SRC (0.47) | KDRSRCKDM4EALDH1A1MAPT | |
| SCHEMBL7005305 | 0.66 | ALDH1A1 (0.44) | LCKKDRTEKSRCKDM4E | |
| SCHEMBL3715556 | 0.66 | CA12 (0.50) | LCKKDRTEKSRCKDM4E | |
| SCHEMBL7009014 | 0.66 | CA12 (0.36) | LCKKDRTEKSRCKDM4E | |
| SCHEMBL20334658 | 0.63 | ALDH1A1 (0.32) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL18269174 | 0.62 | ADORA1 (0.35) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL7574828 | 0.58 | KMT2A (0.55) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL26509801 | 0.57 | CA2 (0.48) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | LCK 3/4885KDR 775/4885TEK 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.