SCHEMBL20335111

SCHEMBL20335111

Cc1ccc(NC(=S)NC(Cc2ccccc2)C(N)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.60
▸ CA2 P00918 3/20 0.60
▸ KMT2A Q03164 4/20 0.51
▸ ALDH1A1 P00352 3/20 0.50
▸ GAA P10253 3/20 0.50
▸ MEN1 O00255 3/20 0.50
▸ ALOX12 P18054 1/20 0.50
▸ MAPK1 P28482 1/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ MAPT P10636 2/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ CCR6 P51684 1/20 0.49
▸ F2 P00734 2/20 0.48
▸ PRSS1 P07477 2/20 0.48
▸ PRSS2 P07478 2/20 0.48
▸ PRSS3 P35030 2/20 0.48
▸ MMP9 P14780 1/20 0.47
▸ PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20335113 1.00 CA1 (0.60) CA1CA2KMT2AALDH1A1GAA
SCHEMBL30317813 0.91 CA1 (0.63) CA1CA2KMT2AALDH1A1GAA
SCHEMBL20335070 0.90 CA1 (0.70) CA1CA2KMT2AALDH1A1GAA
SCHEMBL20335071 0.90 CA1 (0.70) CA1CA2KMT2AALDH1A1GAA
SCHEMBL29686700 0.87 FPR2 (0.60) CA1CA2F2PRSS1PRSS2
SCHEMBL20335158 0.86 GAA (0.59) CA1CA2KMT2AALDH1A1GAA
SCHEMBL20335159 0.86 GAA (0.59) CA1CA2KMT2AALDH1A1GAA
SCHEMBL20334996 0.84 TACR1 (0.60) CA1CA2KMT2AALDH1A1GAA
SCHEMBL20334997 0.84 TACR1 (0.60) CA1CA2KMT2AALDH1A1GAA
SCHEMBL29776967 0.82 HPGD (0.53) CA1CA2KMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 — — EP disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 — — US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 — — US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 CA1 6/4885CA2 116/4885KMT2A 2251/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 CA1 8/4885CA2 89/4885KMT2A 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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