Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20336334 | 0.97 | KIF11 (0.37) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL17625256 | 0.89 | KIF11 (0.33) | KIF11PDK2DUSP3 | |
| SCHEMBL17629727 | 0.89 | KIF11 (0.41) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL17642439 | 0.88 | KIF11 (0.33) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL20348933 | 0.88 | RAB9A (0.34) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL17629730 | 0.85 | ALDH1A1 (0.36) | KIF11PDK2THRBSCN7AKCNH2 | |
| SCHEMBL17625261 | 0.80 | KIF11 (0.35) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL20348937 | 0.80 | KIF11 (0.35) | KIF11PDK2GABRA1GABRB3GABRG2 | |
| SCHEMBL20336340 | 0.79 | HTT (0.45) | THRBLMNASCN7AKCNH2SCN9A | |
| SCHEMBL20355879 | 0.78 | ALDH1A1 (0.32) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | KIF11 2025/4885PDK2 1617/4885GABRA1 1150/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | KIF11 2025/4885PDK2 1617/4885GABRA1 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.