Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38664835 | 0.94 | CA2 (0.57) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL31521545 | 0.85 | ALDH1A1 (0.52) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL29139850 | 0.85 | CA2 (0.41) | CA2ALDH1A1TDP1 | |
| SCHEMBL31434867 | 0.82 | CA2 (0.35) | CA2ALDH1A1TDP1 | |
| SCHEMBL29323570 | 0.81 | LMNA (0.52) | ALDH1A1LMNATDP1TSHRFFAR4 | |
| SCHEMBL31521570 | 0.81 | CA2 (0.42) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL25707195 | 0.81 | ALDH1A1 (0.42) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL11972821 | 0.79 | LMNA (0.50) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL14628150 | 0.79 | CA2 (0.60) | CA2ALDH1A1LMNATDP1TSHR | |
| SCHEMBL252431 | 0.79 | ALDH1A1 (0.57) | CA2ALDH1A1LMNATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9446145-B2 | Curcumin-antibody conjugates as anti-cancer agents | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-09-20 | — | — | US | disclosed |
| US-20130224229-A1 | Novel Curcumin-Antibody Conjugates as Anti-Cancer Agents | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2011068894-A2 | NOVEL CURCUMIN-ANTIBODY CONJUGATES AS ANTI-CANCER AGENTS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224229-A1 | Novel Curcumin-Antibody Conjugates as Anti-Cancer Agents | CD2, H1-5, EPCAM | CA2 438/4885ALDH1A1 231/4885LMNA 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.