SCHEMBL2033732

SCHEMBL2033732

CCOC(=O)Nc1ccc(C#N)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.56
NPC1 O15118 3/20 0.56
HPGD P15428 2/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
LMNA P02545 3/20 0.53
MAPT P10636 3/20 0.53
KDM4E B2RXH2 2/20 0.53
SAE1 Q9UBE0 1/20 0.53
UBA2 Q9UBT2 1/20 0.53
MEN1 O00255 1/20 0.53
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 1/20 0.53
IL18 Q14116 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
TSHR P16473 2/20 0.51
ALDH1A1 P00352 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14376088 0.87 SMN1; SMN2 (0.61) RAB9ANPC1HPGDLMNAMAPT
SCHEMBL7565510 0.86 RAB9A (0.71) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL4773988 0.84 RAB9A (0.63) RAB9ANPC1HPGDLMNAMAPT
SCHEMBL16377564 0.84 RAB9A (0.51) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL29260687 0.84 GAA (0.64) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL9365252 0.84 MAPT (0.65) RAB9AHPGDLMNAMAPTKDM4E
SCHEMBL14349232 0.83 MAPT (0.49) RAB9ALMNAMAPTKDM4ESAE1
SCHEMBL6415967 0.83 SMN1; SMN2 (0.56) RAB9ALMNAMAPTKDM4ESAE1
SCHEMBL842138 0.83 TSHR (0.64) RAB9ALMNAMAPTKDM4ESAE1
SCHEMBL13855057 0.83 NLRP3 (0.49) RAB9ALMNAMAPTKDM4ESAE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023276310-A1 RESIN FILM FOR POLARIZING PLATES, METHOD FOR PRODUCING SAID RESIN FILM, POLARIZING PLATE, AND DISPLAY DEVICE コニカミノルタ株式会社 2023-01-05 WO disclosed
US-8198213-B2 Thermal transfer image receiving sheet and production method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2012-06-12 US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
CN-101326454-B Method for manufacturing polarizing plate, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO INC 2010-11-03 CN disclosed
US-7815823-B2 Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2010-10-19 US disclosed
US-20100136267-A1 THERMAL TRANSFER IMAGE RECEIVING SHEET AND PRODUCTION METHOD OF THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2010-06-03 US disclosed
US-7695762-B2 Thermal transfer image receiving sheet and production method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-04-13 US disclosed
US-20090316084-A1 Method of Producing Polarizing Plate, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-12-24 US disclosed
US-20090286098-A1 Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-11-19 US disclosed
US-20090135345-A1 Polarizing Plate Protective Film, Film Producing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-05-28 US disclosed
US-6337304-B1 HEAT EXCHANGING RECORDING IMAGE RECEIVERS AND DYES KONICA CORPORATION (JP) 2002-01-08 US disclosed
US-20010008749-A1 Silver halide color photographic light sensitive material KONICA CORPORATION (JP) 2001-07-19 US disclosed
EP-1109061-A1 Silver halide color photographic light sensitive material KONICA CORPORATION (JP) 2001-06-20 EP disclosed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 EP disclosed
US-6027867-A HAVING IMPROVED YELLOW COUPLER MOIETY CAPABLE OF COUPLING REACTION WITH AN OXIDATION PRODUCT OF A COLOR DEVELOPING AGENT AND BEING BONDED THROUGH A TRIAZOLE TO AN A-THIOCARBOXYLIC ESTER GROUP; STORAGE STABILITY KONICA CORPORATION (JP) 2000-02-22 US disclosed
US-5807875-A OBESITY THERAPY DR. KARL THOMAE GMBH (DE) 1998-09-15 US disclosed
US-5616620-A HYPOTENSIVE AGENTS KARL THOMAE GMBH (DE) 1997-04-01 US disclosed
EP-0680469-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME Dr. Karl Thomae GmbH (DE) 1995-11-08 EP disclosed
EP-0656562-A2 Diffusion transfer heat processable photosensitive material KONICA CORPORATION (JP) 1995-06-07 EP disclosed
WO-1994017035-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME DR. KARL THOMAE GMBH (DE) 1994-08-04 WO disclosed